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  • Alex A. Khalessi Biography

  • Alexander Khalessi, MD, MBA, the current president of CNS, is chair of the Department of Neurological Surgery, professor of neurological surgery, radiology and neurosciences and the inaugural Don and Karen Cohn Chancellor’s Endowed Chair in Neurosurgery at UC San Diego. As a board-certified neurosurgeon, he specializes in complex cranial surgery, endovascular neurosurgery, stroke care, and neurological oncology.

    Under Dr. Khalessi’s leadership the Department of Neurological Surgery has experienced significant growth. The Department performs an average of 4,000 major cases annually and is one of few health systems in the nation to have two comprehensive stroke centers. The program is consistently ranked in the top 25 best neurology and neurosurgery services in the nation by U.S. News & World Report, and—combined with its sister Department of Neurosciences—is perennially ranked #1 nationally in National Institutes of Health (NIH) funding.

    In addition to his role as president of CNS, Dr. Khalessi champions neurosurgical innovation through several national leadership roles. He is in his fourth term on AANS/CNS’ Washington Committee and sits on the Board of Governors for the American College of Surgeons (ACS). He has served on the CNS Executive Committee since 2014, including as Scientific Program and Annual Meeting Chair, and has held several Executive Committee roles in the Joint AANS/CNS Cerebrovascular Section. 

    A dedicated educator, Dr. Khalessi has directed national and international training courses, including the intermediate resident course for the Society of Neurological Surgeons (SNS). He served on the Accreditation Council for Graduate Medical Education (ACGME), Residency Review Committee (RRC) for Neurological Surgery, and editorial board for the Journal of Graduate Medical Education. Dr. Khalessi also participated in the authorship of the ACGME Neurosurgery and Endovascular Surgical Neuroradiology Milestone Projects.

    Dr. Khalessi has published more than 150 peer-reviewed papers, book chapters and monographs and more than 230 abstracts and presentations. He has served as principal or co-investigator of more than 25 clinical trials and grants. His research has spurred advances in the catheter-based treatment of ischemic stroke, endoscopic treatment of intracerebral hemorrhage, multi-modal treatment of cerebral aneurysms and arteriovenous malformations (AVMs), and complex surgical approaches to brain tumors. Dr. Khalessi’s research interests include the intersection between physiology, engineering, and neurosurgical technique.

    Dr. Khalessi earned his medical degree at Johns Hopkins School of Medicine and completed his neurosurgical residency at the University of Southern California, including an enfolded endovascular neurosurgery fellowship at State University of New York Buffalo. He obtained a bachelor’s degree in public policy and master’s degree in health services research from Stanford University, and holds a master’s degree in business administration from Massachusetts Institute of Technology (MIT) Sloan School of Management.

    Dr. Khalessi resides in San Diego, California, with his wife Sara, a lawyer, and their two young sons.

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