Skip to main content
  • Minimally Invasive Spine Surgery vs Standard Open Surgery for Spinal Metastases, a Retrospective Comparison

    Final Number:

    Murray Echt MD; Rafael De la Garza Ramos MD; Ryan Holland MD; Jonathan P Nakhla MD; Yaroslav Gelfand MD; Phillip Cem Cezayirli MD; Rani Nasser MD; Merritt Drew Kinon MD; Reza Yassari MD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2018 Annual Meeting

    Introduction: Utilizing minimally invasive spine surgery (MISS) for treating spinal metastases causing spinal cord compression and/or instability has great potential, however data supporting the safety and efficacy of MISS over open surgery is still emerging. The aim of this study is to compare outcomes for MISS vs. open surgery for the decompression and stabilization of spinal metastases.

    Methods: This is a single institution retrospective study. Both groups received the same surgical treatment goal including circumferential decompression via laminectomy and transpedicular approach to debulk ventral epidural disease as well as instrumented stabilization. Mean values were compared via unpaired t-tests and proportions via chi-squared tests.

    Results: There were 17 patients in the MISS group and 24 in the open surgery group. The average age of the MISS group was significantly older than the open surgery group (65.5 vs. 56.6; p = 0.026). A significantly higher proportion of patients in the open group had a KPS <70 (54.2% vs 11.8%, p=0.005). This was evidenced by the higher proportion of emergency procedures performed in the open group than the MISS group, 9 out of 24 patients vs. 0 out of 17 patients, respectively. The SINS scores, number of levels fused, and operative parameters including blood transfusions and length of stay were similar, except for the average estimated blood loss for the open surgery vs. the MISS group (783mL vs. 430mL; p = 0.066). The open surgery group experienced 3 complications, including 2 wound infections, and the MISS group had one wound infection. The open surgery group had 2 deaths within 60 days, with both due to other coexisting problems.

    Conclusions: MISS for spinal metastases is a safe and effective approach for decompression and stabilization compared with standard open surgery. Increased ability to perform MISS in emergent settings as well as larger prospective studies are needed.

    Patient Care: Due to the palliative nature of any treatment for patients with spinal metastatic disease, a major goal is to decrease morbidity. Utilizing minimally invasive spine surgery (MISS) has great potential, however widespread use is still emerging. Increased data and discussion of the topic may advance the adoption of the technique, which may prove to replace open surgery as standard of care.

    Learning Objectives: 1) Describe the goals of surgery for spinal metastases 2) Discuss the potential benefits of minimally invasive spine surgery (MISS) 3) Be able to discuss pros and cons of open surgery vs. MISS for individual cases


We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy