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  • Pipeline Embolization Device for Recurrent Cerebral Aneurysms After Microsurgical Clipping

    Final Number:

    Nimer Adeeb; Christoph Johannes Griessenauer MD; Justin M Moore B.Med.Sci (hon), MD, PhD; Christopher J. Stapleton MD; Aman B. Patel MD; Raghav Gupta Medical Student; Apar S Patel MD MPH; Ajith J. Thomas MD; Christopher S. Ogilvy MD

    Study Design:

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2016 Annual Meeting

    Introduction: Microsurgical clipping is regarded as the most durable treatment for cerebral aneurysms. Aneurysm recurrence after clipping is uncommon, and is associated with an increased risk of rupture. Reoperation for recurrent cerebral aneurysms is particularly challenging due to adhesions and scaring, and carries a higher rate of morbidity and mortality. Pipeline embolization as a treatment option for recurrent aneurysms has not been previously reported.

    Methods: A retrospective analysis of patients who underwent Pipeline Embolization Device (PED) placement for recurrent aneurysms after clipping at two major academic institutions in the United States was performed.

    Results: A total of 7 patients were identified. The median time between initial clipping and diagnosis of recurrence was 13 years (range 5-20 years). No morbidity or mortality was associated with PED placement. Complete occlusion was achieved in all patients with imaging follow-up. A history of prior clipping did not affect PED placement or outcome.

    Conclusions: PED for recurrent aneurysms after clipping may be a feasible alternative to reoperation. In our experience, treatment with PED for these aneurysms is safe and efficacious. To our knowledge, this is the first such study to be reported in the literature.

    Patient Care: The use of of pipeline is technically less challenging and is equally effective to re-operation, in treatment of recurrent aneurysms

    Learning Objectives: To determine the safety and efficacy of pipeline use in treatment of recurrent aneurysm after surgical clipping.


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