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  • Cardiac Myxoma Causing Cerebral Metastasis Treated With GKRS –Report of 3 Cases

    Final Number:
    1503

    Authors:
    yeon heo MD; Byung duk kwon; jaesung ahn

    Study Design:
    Other

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2016 Annual Meeting

    Introduction: Cardiac myxoma and myxosacroma is exceptionally rare and distinct disease entity. There is no well established treatment for cerebral metastasis caused by cardiac myxoma and myxosarcoma. We discuss three cases of cardiac myxoma or myxosarcoma causing cerebral metastasis, which was treated with GKRS. This is first case report about brain metastasis of cardiac myxoma which was treated with GKRS. In the cases which described here in , two cases showed multiple expanded mass lesion and the other case showed multiple expanded mass lesion and foramtion of fusiform aneurysm In case of metastatic myxosarcoma , tumor recurrence was observed . But the metastatic myxoma case showed reduction or loss of volume of all lesions. Through these cases, GKRS in treatment of metastatic myxoma was proved to be effective.

    Methods: : Between 2005 and 2009, three patient(1 man and 2 women ) were treated with GKRS for cardiac myxoma brain metastasis . There were multiple metastatic lesion average of five (range 3-6). The mean tumor volume was 242.7 cumm (range 35.1-650 cumm), and the mean marginal dose was 18.7 Gy (range 12-25). Mgagnetic resonance imaging was obtained every 2-6 months following GKRS. Mean follow up duration was 47 months (range 37-56)

    Results: Follow up MRi showed reduction or loss of volume in 11 lesions, recurrence in 3 lesions, local tumor control rate was 78.5%. However, the recurrence occurred only in mxyosarcoma case. In myxoma, all 11 lesions observed a reduction or loss of volune, translate local tumor control of 100% . In myxosarcoma. In myxosarcoma 3 of 5 lesions observed in reduction or loss of the tumr lesions, local tumor control late was 60%.

    Conclusions: GKRS in treatment of metastatic myxoma was proved to be effective

    Patient Care: There is no well established treatment for cerebral metastasis caused by cardiac myxoma and myxosarcoma. This case report will be a good option for guideline of metastatic myxoma or myxosarcoma

    Learning Objectives: To evluate the effect of GKRS for brain metastasis of cardica myxoma (Cardiac myxoma and myxosacroma is exceptionally rare and distinct disease entity. There is no well established treatment for cerebral metastasis caused by cardiac myxoma and myxosarcoma. We discuss three cases of cardiac myxoma or myxosarcoma causing cerebral metastasis, which was treated with GKRS. This is first case report about brain metastasis of cardiac myxoma which was treated with GKRS.)

    References:

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