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  • Is MCS Followed SEP-PR for Locating the Central Sulcus Valid and Precise?

    Final Number:

    Melih Bozkurt MD; Gokmen Kahilogullari MD, PhD; Onur Ozgural; Umit Eroglu; Basak Ceyda Meco; Sukru Caglar

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2015 Annual Meeting

    Introduction: Using neurophysiological stimulating to locate the precentral gyrus and central sulcus for preserving the function allows topmost resection with the possible least morbidity securely. We merged direct monopolar cortical stimulation (MCS) by recording the MEP’s to identify the percentral gyrus with phase reversal of somatosensory evoked potential (SEP-PR) in the present study.

    Methods: Functional mapping of the motor cortex by SEP-PR and MCS was performed in 10 patients (4 males and 6 females aged 16 to 79, mean 56.2 years). The lesions were all located in the neural axis in and around the precentral gyrus. There were 4 (40%) lesions in the left and 6 (6%) in the right hemisphere. Relapse cases were excluded from the study.

    Results: Intra-operative localization of the central sulcus by SEP-PR and functional mapping of the motor cortex by direct MCS followed SEP-PR in all patients. There were no complications observed during stimulation.

    Conclusions: Merging MCS followed SEP-PR for locating the central sulcus and mapping the motor cortex is an accurate and reliable method with 100% sensitivity.

    Patient Care: Accurate mapping of the motor and sensorial cortex for improving resection rates and decrease postoperative hemiparesis after tumor resection.

    Learning Objectives: Preciseness and reliability of MCS followed SEP-PR for locating the central sulcus


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