Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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PE

Risks for Shunt Malfunction in Pediatric Hydrocephalus

May 2, 2016
Pediatrics
By: 
Brandon G. Roque, MD MS
Source: 
Journal of Neurosurgery

The Hydrocephalus Clinical Research Network has conducted a prospective observational study of 1036 initial shunt placements at 6 institutions. They selected 21 variables a priori to evaluate as risk factors for shunt failure. Shunt failure and shunt infection were defined...

SF

Deep Brain Stimulation Efficacious for Treatment Resistant Depression

May 2, 2016
Stereotactic & Functional
By: 
Shervin Rahimpour, MD
Shivanand P. Lad, MD, PhD
Source: 
JAMA Psychiatry

Deep Brain Stimulation (DBS) is an evolving therapy for psychiatric disorders, specifically treatment-resistant depression (TRD). In this study by Bergfeld and colleagues, stimulation of the ventral anterior limb of the internal capsule (vALIC) for TRD is revisited with a more...

TU

Radiation plus PCV improves long-term overall survival in patients with low grade glioma

May 2, 2016
Tumor
By: 
Nader Sanai, MD
Source: 
New England Journal of Medicine

As a follow-up to the 2012 results of a randomized Phase III trial adding procarbazine, lomustine (CCNU), and vincristine (PCV) chemotherapy after radiotherapy for newly-diagnosed patients with WHO grade II glioma, this new report details the long-term results after 12...

PE

Pediatric Moyamoya Outcomes Are Better in High Volume Centers

May 2, 2016
Pediatrics
By: 
Robert M. Starke, MD MSC
Source: 
Stroke

Comprehensive data on the optimal treatment of and outcomes in pediatric moyamoya in the US is lacking.  Titsworth et al. assessed a total of 2454 moyamoya admissions from 1997 to 2012 in the Kids Inpatient Database.  The authors found that...

SP

Randomized trials of lumbar fusion in addition to laminectomy for lumbar stenosis.

May 2, 2016
Spine
By: 
Justin Slavin, MD
Source: 
New England Journal of Medicine

Two randomized controlled studies were recently published that challenge the notion that instrumented fusion as an adjuvant to surgical decompression improves outcome when treating lumbar spinal stenosis. Forsth et al. randomized patients with symptomatic one and two-level lumbar stenosis with...

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