Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
Search Neurosurgery Watch
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National Patterns of Carotid Revascularization Before and After the Carotid Revascularization Endarterectomy vs Stenting Trial (CREST)

February 1, 2018
Cerebrovascular
By: 
Stephen Grupke, MD

CREST demonstrated subtle advantage of carotid endarterectomy (CEA) compared to carotid artery stenting (CAS) in subgroup analysis. Specifically, patients receiving CEA had lower rates of stroke despite no difference in composite outcomes which included myocardial ischemia. In the present study,...

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DEFUSE 3: Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

February 1, 2018
Cerebrovascular
By: 
Andrew W. Grande, MD
Shailesh Male, MD

DEFUSE-3 is a randomized clinical trial comparing endovascular therapy and standard medical management with medical management alone in anterior circulation large vessel occlusion (LVO) acute ischemic stroke (AIS) patients presenting within 6 to 16 hours from last well-known time with...

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Endoscopic Treatment versus Shunting for Infant Hydrocephalus

January 1, 2018
Pediatrics
By: 
Raheel Ahmed, MD, PhD
Source: 
NEJM

Endoscopic treatment of hydrocephalus in developing countries enables effective CSF diversion. Yet, several studies have demonstrated relative ventriculomegaly despite successful CSF shunting in patients undergoing endoscopic third ventriculostomy and choroid plexus cauterization (ETV-CPC) versus ventriculoperitoneal shunting (VPS). The secondary effects...

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Guidelines for Post-thrombectomy Management of ELVO Patients

December 4, 2017
Cerebrovascular
By: 
Michelle J. Smith, MD
Source: 
NCBI

Patients with emergent large vessel occlusions (ELVO) benefit from mechanical thrombectomy and appropriate postoperative care is necessary to optimize outcomes.  Recent SNIS guidelines covered post-thrombectomy care, ischemic penumbra, therapeutic hypertension, complication management, malignant cerebral edema, access site complications, and rehabilitation. ...

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DAWN Trial: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

December 4, 2017
Cerebrovascular
By: 
Andrew W. Grande, MD
Shailesh Male, MD
Source: 
NEJM

In 2015, five major randomized controlled trials showed that thrombectomy for anterior large vessel ischemic strokes within 6 hours provided benefit. What about patients who present beyond 6 hours? The DAWN a multicenter, prospective, randomized, open-label, blinded endpoint trial was...

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