Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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rhBMP-2 Increases Fusion Rates and Immediate Postoperative Pain after Spinal Fusion: A Meta-Analysis

September 2, 2013
Spine
By: 
John H. Shin, MD
Source: 
Annals of Internal Medicine

The Annals of Internal Medicine recently published a meta-analysis of the safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion, regardless of spinal level or surgical approach. Given the rise in spinal fusions and the increased use...

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Effectiveness and Harms of Recombinant Human Bone Morphogenetic Protein-2 in Spine Fusion

September 2, 2013
Spine
By: 
John H. Shin, MD
Source: 
Annals of Internal Medicine

A systematic review and meta-analysis of complications associated with rhBMP-2 was recently published in the Annals of Internal Medicine. Given the historical under-reporting of complications associated with the use of rhBMP-2, neurosurgeons are encouraged to examine the data presented in...

Prevalence of Unruptured Aneurysms in Healthy Asymptomatic Patients

September 2, 2013
By: 
Justin F. Fraser, MD
Source: 
Springer

Previous studies examining the prevalence of unruptured intracranial aneurysms (UIAs) report a range of 0.8-8.4%. Given this high variance, Harada et al. (Acta Neurochir, August 2013[online]) conducted a review of healthy asymptomatic adult patients who underwent MRA over 2 years...

Three Clinical Trials of Endovascular Therapy for Ischemic Stroke

August 1, 2013
By: 
Alexander A. Khalessi, MD

Editor’s note: The CNS, AANS, SVIN, SNIS & ASNR-endorsed joint response to these 3 clinical trials is available at Neurosurgery®.

IMS III was a randomized controlled clinical trial involving 656 iv-tPA eligible participants with presenting NIH Stroke Scales greater than 8....

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Headaches After Craniotomy Versus Endovascular Therapy for Aneurysms

August 1, 2013
Cerebrovascular, Pain
By: 
Justin F. Fraser, MD
Source: 
Wiley Online Library

Headaches can significantly impact quality of life after aneurysm treatment. Magalhães JE et al. (Headache, June 2013) performed a 4-month prospective cohort study comparing headaches in aneurysm patients after surgical clipping or endovascular coiling using the International Classification of Headache...

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