Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Madison, Wisconsin
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
Search Neurosurgery Watch

Clazosentan Reduced Vasospasm-Related Morbidity but Did Not Improve aSAH Neurological Outcomes

July 10, 2013
By: 
Yin C. Hu, MD
Source: 
Journal of Neurosurgery

Cerebral vasospasm secondary to aneurysmal subarachnoid hemorrhages (aSAH) causes significant cause of morbidity and mortality. Clazosentan is an endothelin receptor antagonist that inhibits endothelin-mediated vasoconstriction, and is being tested clinically for preventing vasospasm. A meta-analysis by Shen et al (J....

TU

Maximizing Resection Correlate with Positive Prognosis for Adult WHO Grade II Gliomas at Diagnosis and Recurrence

July 10, 2013
Tumor
By: 
John S. Kuo, MD PhD
Source: 
Journal of Neurosurgery

The largest modern series of 1097 WHO Grade II gliomas (with MRI-verified tumor sizes) collected by the multi-center French Glioma Research Group from January 1985 to December 2007 (mean 7.4 year follow-up) was reported in Journal of Neurosurgery (June 2013)....

Surgery for Symptomatic Thalamic and Brainstem Cavernous Malformations

July 10, 2013
By: 
Andrew W. Grande, MD

Three recent articles in World Neurosurgery (May-June 2013) address cavernoma resection in eloquent brain regions such as thalamus and brainstem. They emphasize complete resection of symptomatic brainstem and thalamic cavernomas with appropriate surgical approach and use of adjunct fiberoptic CO2...

SP

New Guidelines for the Management of Acute Cervical Spine and Spinal Cord Injury

May 15, 2013
Spine
By: 
Nathaniel P. Brooks, MD
Source: 
http://journals.lww.com/neurosurgery/toc/2013/03002

The cervical spine is vulnerable because of its anatomical mobility and complexity. These features also make cervical trauma management difficult and nuanced. Management decisions are made with the aid of experience, evidence and patient input. In order to improve our...

Earlier DBS Treatment Is Beneficial for Selected Parkinson’s Disease Patients

May 15, 2013
By: 
Nader Pouratian, MD PhD
Source: 
The New England Journal of Medicine

Previous randomized controlled trials established the efficacy of deep brain stimulation (DBS) for patients with advanced Parkinson’s disease (PD), but does DBS have a role earlier in the disease course? The New England Journal of Medicine (Feb. 14, 2013) reported...

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