Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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Cancer Risk After Use of Recombinant Bone Morphogenic Protein-2 for Spinal Arthrodesis

October 1, 2013
Spine
By: 
Farbod Asgarzadie, MD
Source: 
The Journal of Bone & Joint Surgery

Carragee and colleagues recently published an analysis of publicly available raw data from the Medtronic sponsored AMPLIFY study (a randomized controlled trial of patients with degenerative lumbar disease who underwent a single-level instrumented posterolateral arthrodesis with either high-dose BMP or...

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Comparison of Coflex Interlaminar Stabilization With Open Instrumented Fusion After Decompression for Spinal Stenosis and Low-Grade Degenerative Spondylolisthesis

October 1, 2013
Spine
By: 
Yi Lu, MD PhD
Source: 
http://journals.lww.com/spinejournal/pages/articleviewer.aspx?year=2013&issue=08...

Davis et al. reported results of a prospective randomized multicenter trial (322 patients were enrolled from 21 sites) comparing decompression and Coflex interlaminar stabilization (Coflex) vs. traditional open decompression and instrumented posterior spinal fusion (PSF) for spinal stenosis and grade...

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Risk Factors for Vertebral Compression Fractures After Stereotactic Radiotherapy for Spinal Metastases

October 1, 2013
Spine, Tumor
By: 
Clark C. Chen, MD PhD
Joseph D. Ciacci, MD
Source: 
Journal of Clinical Oncology

Vertebral compression fractures (VCF) are an adverse event after stereotactic body radiotherapy (SBRT) or radiosurgery for spinal metastases. A recent Journal of Clinical Oncology report retrospectively reviewed the SBRT experience at MD Anderson Cancer Center, Cleveland Clinic, and University of...

Effect of White-Matter Lesions on Peri-Procedural Stroke Risk After Carotid Artery Stenting Versus Endarterectomy

October 1, 2013
By: 
Alexander A. Khalessi, MD
Source: 
The Lancet

Pre-procedural white matter changes as a predictive factor for stroke within 30 days of carotid artery stenting (CAS) versus carotid endarterectomy (CEA) was tested in analyzing the International Carotid Stenting Study (ICSS), a multicenter, double-blinded randomized clinical trial treating symptomatic...

Time Course and Factors Affecting Long-Term Recovery After Poor-Grade SAH

October 1, 2013
By: 
Yin C. Hu, MD
Source: 
Journal of Neurosurgery

The incidence and factors predicting long term neurological improvement and recovery of patients with poor-grade aneurysmal subarachnoid hemorrhage (SAH) are reported by Wilson et al in a cohort study of 88 poor-grade SAH patients from the Barrow Ruptured Aneurysm Trial...

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