Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Madison, Wisconsin
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
Search Neurosurgery Watch

Anti-Seizure Prophylaxis Does Not Prevent Seizures After Aneurysmal SAH

July 10, 2013
By: 
William J. Mack, MD
Source: 
http://www.sciencedirect.com/science/article/pii/S187887501200900X

Seizures are a well-recognized occurrence after aneurysmal subarachnoid hemorrhage (aSAH). However, incidence rates vary within the reported literature and controversy exists regarding the utility of prophylactic antiepileptic drug (AED) administration. In the May/June 2013 issue of World Neurosurgery, Raper and...

The Barrow Ruptured Aneurysm Trial: 3-Year Results

July 10, 2013
By: 
Stacey Quintero Wolfe, MD
Source: 
Journal of Neurosurgery

The 3-year results of the Barrow Ruptured Aneurysm Trial (BRAT), an intention-to-treat study comparing safety and efficacy of microsurgical clip occlusion versus endovascular coil embolization for aSAH patients, were reported in J. Neurosurgery (July 2013). Secondary analyses included outcome based...

Clazosentan Reduced Vasospasm-Related Morbidity but Did Not Improve aSAH Neurological Outcomes

July 10, 2013
By: 
Yin C. Hu, MD
Source: 
Journal of Neurosurgery

Cerebral vasospasm secondary to aneurysmal subarachnoid hemorrhages (aSAH) causes significant cause of morbidity and mortality. Clazosentan is an endothelin receptor antagonist that inhibits endothelin-mediated vasoconstriction, and is being tested clinically for preventing vasospasm. A meta-analysis by Shen et al (J....

Earlier DBS Treatment Is Beneficial for Selected Parkinson’s Disease Patients

May 15, 2013
By: 
Nader Pouratian, MD PhD
Source: 
The New England Journal of Medicine

Previous randomized controlled trials established the efficacy of deep brain stimulation (DBS) for patients with advanced Parkinson’s disease (PD), but does DBS have a role earlier in the disease course? The New England Journal of Medicine (Feb. 14, 2013) reported...

SP

New Guidelines for the Management of Acute Cervical Spine and Spinal Cord Injury

May 15, 2013
Spine
By: 
Nathaniel P. Brooks, MD
Source: 
http://journals.lww.com/neurosurgery/toc/2013/03002

The cervical spine is vulnerable because of its anatomical mobility and complexity. These features also make cervical trauma management difficult and nuanced. Management decisions are made with the aid of experience, evidence and patient input. In order to improve our...

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