Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Madison, Wisconsin
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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Radiosurgical Management of Non-Functional Pituitary Adenomas

October 1, 2013
Stereotactic & Functional, Tumor
By: 
Gavin P. Dunn, MD PhD
Gabriel Zada, MD
Source: 
Journal of Neurosurgery

The North American Gamma Knife Consortium reported outcomes following gamma knife radiosurgery (GKRS) for nonfunctioning pituitary adenomas in 512 patients (93.6% with prior surgical resection) with median 36 months followup (range 1-223 months) and median tumor margin dose of 16...

Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor

October 1, 2013
By: 
Andrew H. Marky, MD
Shivanand P. Lad, MD, PhD
Source: 
The New England Journal of Medicine

An open-label, uncontrolled pilot study using transcranial MRI-guided focused ultrasound thalamotomy for essential tremor was recently published by Elias et al in the New England Journal of Medicine. The unilateral ventral intermediate (VIM) nucleus of the thalamus was targeted, with...

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rhBMP-2 Increases Fusion Rates and Immediate Postoperative Pain after Spinal Fusion: A Meta-Analysis

September 2, 2013
Spine
By: 
John H. Shin, MD
Source: 
Annals of Internal Medicine

The Annals of Internal Medicine recently published a meta-analysis of the safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion, regardless of spinal level or surgical approach. Given the rise in spinal fusions and the increased use...

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Effectiveness and Harms of Recombinant Human Bone Morphogenetic Protein-2 in Spine Fusion

September 2, 2013
Spine
By: 
John H. Shin, MD
Source: 
Annals of Internal Medicine

A systematic review and meta-analysis of complications associated with rhBMP-2 was recently published in the Annals of Internal Medicine. Given the historical under-reporting of complications associated with the use of rhBMP-2, neurosurgeons are encouraged to examine the data presented in...

Prevalence of Unruptured Aneurysms in Healthy Asymptomatic Patients

September 2, 2013
By: 
Justin F. Fraser, MD
Source: 
Springer

Previous studies examining the prevalence of unruptured intracranial aneurysms (UIAs) report a range of 0.8-8.4%. Given this high variance, Harada et al. (Acta Neurochir, August 2013[online]) conducted a review of healthy asymptomatic adult patients who underwent MRA over 2 years...

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