Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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Evidence-Based Guideline Update: Vagus Nerve Stimulation for the Treatment of Epilepsy

November 1, 2013
Pain
By: 
Jason M. Schwalb, MD
Source: 
PubMed

In the October 2013 issue of Neurology, Morris and colleagues authored an AAN and AES-supported guideline regarding vagal nerve stimulation. There was only one paper, the initial pivotal trial, that was felt to be better than Class III evidence. All...

Predictive Factors of Outcome in Primary Cervical Dystonia Following Pallidal Deep Brain Stimulation

November 1, 2013
By: 
Jason M. Schwalb, MD
Source: 
PubMed

Witt et al. report the UCSF and Toronto Western Hospital experiences with GPi DBS for cervical dystonia. Patients with cranial involvement or mild upper extremity dystonia were not excluded. With 28 patients, this is the largest retrospective cohort in the...

Pilot Study of Focused Ultrasound Thalamotomy for Essential Tremor

October 1, 2013
By: 
Andrew H. Marky, MD
Shivanand P. Lad, MD, PhD
Source: 
The New England Journal of Medicine

An open-label, uncontrolled pilot study using transcranial MRI-guided focused ultrasound thalamotomy for essential tremor was recently published by Elias et al in the New England Journal of Medicine. The unilateral ventral intermediate (VIM) nucleus of the thalamus was targeted, with...

SP

Cancer Risk After Use of Recombinant Bone Morphogenic Protein-2 for Spinal Arthrodesis

October 1, 2013
Spine
By: 
Farbod Asgarzadie, MD
Source: 
The Journal of Bone & Joint Surgery

Carragee and colleagues recently published an analysis of publicly available raw data from the Medtronic sponsored AMPLIFY study (a randomized controlled trial of patients with degenerative lumbar disease who underwent a single-level instrumented posterolateral arthrodesis with either high-dose BMP or...

SP

Comparison of Coflex Interlaminar Stabilization With Open Instrumented Fusion After Decompression for Spinal Stenosis and Low-Grade Degenerative Spondylolisthesis

October 1, 2013
Spine
By: 
Yi Lu, MD PhD
Source: 
http://journals.lww.com/spinejournal/pages/articleviewer.aspx?year=2013&issue=08...

Davis et al. reported results of a prospective randomized multicenter trial (322 patients were enrolled from 21 sites) comparing decompression and Coflex interlaminar stabilization (Coflex) vs. traditional open decompression and instrumented posterior spinal fusion (PSF) for spinal stenosis and grade...

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