Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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CV

“ReCCLAIM I”: endovascular reperfusion and hypothermia for severe ischemic stroke

March 29, 2014
Cerebrovascular
By: 
Michelle J. Smith, MD
Source: 
J NeuroIntervent

Horn et al. report a prospective Phase I trial to assess hypothermia in severe cerebral infarction patients treated with mechanical thrombectomy. Although preclinical studies showed improved outcomes with hypothermia, clinical studies performed on a heterogeneous patient population failed to show...

TU

Two Phase III trials do not show improved GBM survival with addition of bevacizumab

March 29, 2014
Tumor
By: 
Nader Sanai, MD

The New England Journal of Medicine (Feb ‘14) reported results from two randomized, double-blind, placebo-controlled Phase III trials testing addition of bevacizumab (BEV) to standard radiation + temozolomide therapy for newly-diagnosed glioblastoma (GBM): Radiation Therapy Oncology Group 0825 and ‘Avastin...

CV

Fatal Intracerebral Hemorrhage After Pipeline Embolization of Aneurysm: Histopathological Analysis

February 28, 2014
Cerebrovascular
By: 
Stacey Quintero Wolfe, MD
Source: 
Journal of Neurosurgery

Delayed ipsilateral intraparenchymal hemorrhage following aneurysm treatment with the Pipeline Embolization Device has been observed in multiple studies without a clear etiology. This important study demonstrates convincing histopathological evidence of foreign material occluding small vessels within the hemorrhagic area in...

Public Reporting of Surgical Outcomes: Position Statement and Recommendations

February 28, 2014
By: 
Nader Pouratian, MD PhD
Source: 
Surgical Quality Alliance

Public reporting of health care outcomes and utilization is increasingly expected by patients, purchasers, regulatory authorities, as well as physicians. Despite its clear potential to positively impact health care quality improvement efforts, most reporting standards and guidance focus on primary...

SF
TU

Predicting Overall Survival for Patients After Radiosurgery for Brain Metastases

February 3, 2014
Stereotactic & Functional, Tumor
By: 
Gavin P. Dunn, MD PhD
Gabriel Zada, MD
Source: 
Journal of Neurosurgery

Difficulties in predicting survival for brain metastasis patients is underappreciated and has ramifications for cost-effective care. Kondziolka et al. assessed the ability of clinicians to predict survival in 150 cancer patients undergoing stereotactic radiosurgery for brain metastases from 2009-11. Clinicians...

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