Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Madison, Wisconsin
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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Effect of Anesthesia on Outcomes of Endovascular Thrombectomy: A Randomized Clinical Trial

February 1, 2017
Cerebrovascular
By: 
Michelle J. Smith, MD
Source: 
JAMA

Mechanical thrombectomy in select patients with acute ischemic stroke is a proven treatment. However, optimal anesthesia during this procedure is debated. Schonenberger et al. performed a prospective, randomized, blinded outcome trial assessing the use of general endotracheal anesthesia versus conscious...

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Endovascular thrombectomy after large-vessel ischemic stroke: a meta-analysis of individual patient data from five randomised trials

February 1, 2017
Cerebrovascular
By: 
Robert Starke, MD, MSc
Source: 
Lancet

 In 2015, five randomized trials showed efficacy of endovascular thrombectomy over medical care in patients with acute ischemic stroke caused by large vessel occlusion (LVO) of arteries of the proximal anterior circulation. A recent publication in the Lancet from the trial investigators from these trials, reported the pooled patient analysis of these studies...

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Guidelines for Severe Traumatic Brain Injury: 4th edition

January 10, 2017
Trauma
By: 
Roand Torres, MD
Source: 
Neurosurgery

Approximately 2.5 million Americans annually suffer traumatic brain injury (TBI). Severe TBI causes more than 30 percent of all injury-related deaths in the U.S. and account for 90 percent of the nearly $80 billion in annual costs. The new Guidelines...

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RESCUEicp Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension

January 10, 2017
Trauma
By: 
Roand Torres, MD
Source: 
New Eng J Med

Hutchinson et al. recently reported on the Randomised Evaluation of Surgery with Craniectomy for Uncontrollable Elevation of Intracranial Pressure (RESCUEicp) trial, comparing unilateral or bilateral decompressive craniectomy with...

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VAPOUR - A Randomized-Controlled Study of Vertebroplasty for Acute Painful Osteoporotic Fractures

November 30, 2016
Spine
By: 
Justin Slavin, MD
Source: 
The Lancet (2016) 388: 1408-16

Two prior RCTs showed no benefit for vertebroplasty compared to non-surgical management of osteoporotic fractures up to 12 months after onset. The VAPOUR study is a randomized, placebo-controlled, double-blinded trial to assess effectiveness of vertebroplasty for acute fractures. 120 patients...

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