Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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PE

Comparison of ETV/CPC versus ETV alone versus VP shunt alone in infants

April 2, 2018
Pediatrics
By: 
Brandon G. Rocque, MD MS
Source: 
Journal of Neurosurgery, Pediatrics

This study from the Hydrocephalus Clinical Research Network is the first prospective, multi-institution comparison of endoscopic third ventriculostomy with choroid plexus cauterization (ETV/CPC) to ventriculoperitoneal shunting (VPS) in North America. 118 infants under 2 years old (adjusted age for those...

PE

Reinfection after treatment of first shunt infection: a prospective observational cohort study

April 2, 2018
Pediatrics
By: 
Raheel Ahmed, MD, PhD
Source: 
Journal of Neurosurgery, Pediatrics

CSF shunt re-infection rates are approximately 2-3 fold higher following an initial infection. Data from 7 participating centers of the Hydrocephalus Clinical Research Network was used to evaluate how clinical management of initial CSF shunt infections affects reinfection rates. Overall...

SP

Contralateral C7 Nerve Root Transfer Restores Hand Function After Cerebral Injury

March 1, 2018
Spine
By: 
Allan D. Levi, MD PhD
S. Shelby Burks, MD
Source: 
NEJM

CNS injury can lead to spastic upper extremity paralysis. Results of a prospective, randomized, single-blind controlled trial testing efficacy of nerve transfer with the contralateral C7 nerve root into the paralyzed limb in patients with central cerebral injury were reported...

TU

Tumor-treating fields plus temozolomide versus temozolomide alone for GBM patients

February 1, 2018
Tumor
By: 
Jonathan Sherman, MD
J. Bradley Elder, MD
Source: 
JAMA

Standard adjuvant therapy after GBM resection is radiation therapy (RT) with concomitant temozolomide (TMZ) followed by maintenance TMZ. Tumor-treating fields (TTFields), consisting of low-intensity, alternating electric fields delivered via transducer arrays applied to the scalp. Addition of tumor-treating fields to...

TU

Guidelines for Vestibular Schwannoma Management

February 1, 2018
Tumor
By: 
Jonathan Sherman, MD
J. Bradley Elder, MD
Source: 
Neurosurgery

Managing vestibular schwannoma patients requires a multidisciplinary team approach that incorporates neurosurgery, otolaryngology, and radiation oncology. Neuro-radiology, pathology, intra-operative monitoring, and neuro-oncology are also important components. The Guidelines for the Treatment of Adults with Vestibular Schwannoma were recently introduced, providing...

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