Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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PE

Continuous EEG in subclinical seizures in moderate to severe pediatric TBI

August 31, 2015
Pediatrics
By: 
Brandon G. Rocque, MD, MS
Source: 
JNS Peds

The impact of sub-clinical seizures on outcomes and management of adult head injury have been studied extensively. In this study, children with moderate or severe TBI (GCS 3-12), admitted to Children’s Hospital of Colorado, underwent at least 48 hours of...

TU

Genomic Analysis Identifies New Prognostic Molecular Subtypes of Diffuse Lower-Grade Gliomas

July 30, 2015
Tumor
By: 
Nader Sanai, MD
Source: 
NEJM

The Cancer Genome Atlas Research Network characterized low-grade gliomas through a genome-wide analysis of 293 previously-untreated adult lower-grade glioma: oligodendrogliomas (n=116), astrocytomas (n=100), and oligoastrocytomas (n=77).  Overall, data from DNA copy number, RNA, and DNA methylation status demonstrated three distinct...

PE

Improvement of Tuberous Sclerosis Epilepsy Outcomes via Resection of Symptomatic Tuber Plus Adjacent Zone

July 30, 2015
Pediatrics
By: 
Brandon G. Rocque, MD, MS
Source: 
Neurosurgery

Tuberous sclerosis complex (TSC) is a frequent etiology for childhood epilepsy surgery evaluation. A retrospective, multicenter cohort, including 78 patients from 6 centers in the United States and Canada was studied to identify predictors of seizure outcome in children with...

SP

Two level cervical arthroplasty is as effective and safe as one level case

June 29, 2015
Spine
By: 
Yi Lu, MD PhD
Source: 
Spine

One level arthroplasty has been shown to be a safe alternative to one level anterior cervical diskectomy and fusion in selected patients with similarly excellent outcome. It has an added potential benefit of reducing the adjacent segment degeneration. Multi-level cervical...

CV

Superiority of thrombectomy within 8 hours of anterior circulation large vessel occlusion over medical therapy

June 29, 2015
Cerebrovascular
By: 
Alexander A. Khalessi, MD
Source: 
The New England Journal of Medicine

REVASCAT was a multicenter randomized controlled trial enrolling patients within 8 hours of symptom onset and confirmed anterior circulation, large vessel occlusion.  Patients were randomized to medical therapy versus medical therapy plus thrombectomy with the Solitaire FR Stent Retriever device....

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