Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Madison, Wisconsin
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations

May 2, 2017
Cerebrovascular
By: 
Stephen Grupke, MD
Source: 
Pubmed

This report addresses 5 key topics for cerebral cavernous malformations: epidemiology and natural history, genetic testing and counseling, diagnostic criteria and radiology standards, neurosurgical considerations, and neurologic considerations.  Search terms were derived for each key topic by the Angioma Alliance...

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2 Year Outcomes of MR CLEAN trial for ischemic stroke

May 2, 2017
Cerebrovascular
By: 
Robert Starke, MD, MSc
Source: 
The New England Journal of Medicine

Several trials involving patients with acute ischemic stroke and large vessel occlusion have shown better short-term functional outcomes with endovascular treatment than with conventional treatment.  Recently, the MR CLEAN Investigators published 2 year outcomes from patients randomized to receive either...

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Anterior ventricular catheter entry site associated with lower shunt failure risk

March 1, 2017
Pediatrics
By: 
Brandon G. Roque, MD MS
Source: 
Journal of Neurosurgery: Pediatrics

A study by the Hydrocephalus Clinical Research Network (HCRN) used data from 3 previous trials to determine the optimal position of ventricular catheter tips in ventriculoperitoneal shunts. Positioning of ventricular catheter tips were defined with 5 parameters: tip location (frontal...

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Hemorrhage risk and Radiosurgery outcomes for Pediatric AVM

March 1, 2017
Cerebrovascular, Pediatrics, Stereotactic & Functional
By: 
Brandon G. Rocque, MD, MS
Source: 
Journal of Neurosurgery

The International Gamma Knife Research Foundation presented 2 pediatric brain arteriovenous malformations (AVM) reports: 1) the incidence and risk for hemorrhagic presentation, and 2) radiosurgery outcomes. Retrospective review of 357 patients (mean age of 12.6 years) from 7 centers: all...

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The Optimal Timing of Endovascular Thrombectomy For Ischemic Stroke: A Meta-analysis

February 1, 2017
Cerebrovascular
By: 
Stephen Grupke, MD
Source: 
JAMA

Saver et al. analyzed pooled data of 1,287 patients from five large randomized phase 3 trials evaluating the use of mechanical thrombectomy vs medical management in the emergent treatment of acute ischemic stroke secondary to large vessel occlusion (MR CLEAN,...

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