Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
Search Neurosurgery Watch
PE

Complications following pediatric cranioplasty after decompressive craniectomy: a multicenter retrospective study

November 1, 2018
Pediatrics
By: 
Raheel Ahmed, MD, PhD
Source: 
Journal of Neurosurgery: Pediatrics

Renewed focus on neurosurgical health care quality metrics dictates critical evaluation of current practices and their impact on postoperative complications, hospital costs and patient outcomes. Cranioplasty procedures in both adult and pediatric patients have been traditionally been associated with significant...

TU

Clinical trial of dual immunotherapy agents for melanoma brain metastase

September 10, 2018
Tumor
By: 
Matthew Hunt, MD.
Source: 
NJEM

The study by Tawbi et al. published in the New England Journal of Medicine in late August examines the effects of dual-agent immunotherapy on intracranial metastatic disease. This open-label Phase II trial uses nivolumab and ipilimumab to treat patients with...

CV

Comparison of General Anesthesia vs. Conscious Sedation during Endovascular Therapy on Infarct Growth and Clinical Outcomes in Acute Ischemic Stroke

August 2, 2018
Cerebrovascular
By: 
Stephen Grupke, MD
Source: 
Neurosurgery

Previous studies have yielded conflicting results regarding patient outcomes after endovascular therapy for acute ischemic stroke depending on whether general anesthesia (GA) or conscious sedation (CS) was administered. The GOLIATH trial (General or Local Anesthesia in Intra Arterial Therapy) is...

PA
SP

Bupivacaine Field Block with Clonidine for Postoperative Pain Control in Posterior Spine Approaches: A Randomized Double-Blind Trial

August 2, 2018
Pain, Spine
By: 
Kelsey Hundley, MD
Erika Petersen, MD
Source: 
Neurosurgery

This double-blind study of 225 patients at a single center undergoing posterior cervical or lumbar surgery by the same surgeon demonstrated improved postoperative pain control when 150 ug clonidine was added to 20mL of bupivacaine for pre-incisional field block compared...

CV

Restenosis & risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study: secondary analysis of a RCT

July 5, 2018
Cerebrovascular
By: 
Stephen Grupke, MD
Source: 
Lancet Neurology

The International Carotid Stenting Study examined 1713 patients across 50 centers with symptomatic carotid stenosis (50% or greater) who were randomized to angioplasty and stenting vs endarterectomy in a 1:1 ratio.  Patients were followed at 30 days, 6 months, and...

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