Updated Guidelines for Fusion in Managing Degenerative Lumbar Spine Disease

Journal of Neurosurgery

Release of updated evidenced-based guidelines for the surgical care of degenerative lumbar spinal conditions by the CNS/AANS Spine Section includes relevant literature since the 2005 published guidelines, and a 5-tier level of evidence approach for the 16 subtopics was used for objective evidence distinctions. Forty-five updated recommendations (Grades “A” to “C” and “I” for insufficient) are provided based on the supporting evidence strength. Key highlights include analysis of new health-related and economic outcome studies following (i) fusion for stenosis with/without spondylolisthesis and (ii) use of bone graft extenders and substitutes. This rigorous synthesis of the best available current evidence is an invaluable reference.

S. R. Manoharan, MBBS
Columbus, OH
H. Francis Farhadi, MD PhD
Columbus, OH