Spine & Peripheral Nerve

Read the latest on spine-related findings and techniques in Neurosurgery Watch.

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Risk Factors for Vertebral Compression Fractures After Stereotactic Radiotherapy for Spinal Metastases

October 1, 2013
Spine, Tumor
By: 
Clark C. Chen, MD PhD
Joseph D. Ciacci, MD
Source: 
Journal of Clinical Oncology

Vertebral compression fractures (VCF) are an adverse event after stereotactic body radiotherapy (SBRT) or radiosurgery for spinal metastases. A recent Journal of Clinical Oncology report retrospectively reviewed the SBRT experience at MD Anderson Cancer Center, Cleveland Clinic, and University of...

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Comparison of Coflex Interlaminar Stabilization With Open Instrumented Fusion After Decompression for Spinal Stenosis and Low-Grade Degenerative Spondylolisthesis

October 1, 2013
Spine
By: 
Yi Lu, MD PhD
Source: 
http://journals.lww.com/spinejournal/pages/articleviewer.aspx?year=2013&issue=08...

Davis et al. reported results of a prospective randomized multicenter trial (322 patients were enrolled from 21 sites) comparing decompression and Coflex interlaminar stabilization (Coflex) vs. traditional open decompression and instrumented posterior spinal fusion (PSF) for spinal stenosis and grade...

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Cancer Risk After Use of Recombinant Bone Morphogenic Protein-2 for Spinal Arthrodesis

October 1, 2013
Spine
By: 
Farbod Asgarzadie, MD
Source: 
The Journal of Bone & Joint Surgery

Carragee and colleagues recently published an analysis of publicly available raw data from the Medtronic sponsored AMPLIFY study (a randomized controlled trial of patients with degenerative lumbar disease who underwent a single-level instrumented posterolateral arthrodesis with either high-dose BMP or...

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Effectiveness and Harms of Recombinant Human Bone Morphogenetic Protein-2 in Spine Fusion

September 2, 2013
Spine
By: 
John H. Shin, MD
Source: 
Annals of Internal Medicine

A systematic review and meta-analysis of complications associated with rhBMP-2 was recently published in the Annals of Internal Medicine. Given the historical under-reporting of complications associated with the use of rhBMP-2, neurosurgeons are encouraged to examine the data presented in...

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rhBMP-2 Increases Fusion Rates and Immediate Postoperative Pain after Spinal Fusion: A Meta-Analysis

September 2, 2013
Spine
By: 
John H. Shin, MD
Source: 
Annals of Internal Medicine

The Annals of Internal Medicine recently published a meta-analysis of the safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion, regardless of spinal level or surgical approach. Given the rise in spinal fusions and the increased use...

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New Guidelines for the Management of Acute Cervical Spine and Spinal Cord Injury

May 15, 2013
Spine
By: 
Nathaniel P. Brooks, MD
Source: 
http://journals.lww.com/neurosurgery/toc/2013/03002

The cervical spine is vulnerable because of its anatomical mobility and complexity. These features also make cervical trauma management difficult and nuanced. Management decisions are made with the aid of experience, evidence and patient input. In order to improve our...

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