Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

Please contact us with any suggestions or comments.

John S. Kuo, MD PhD FACS
Madison, Wisconsin
Co-Editor
Nader Pouratian, MD PhD
Los Angeles, California
Co-Editor
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CV

The Optimal Timing of Endovascular Thrombectomy For Ischemic Stroke: A Meta-analysis

February 1, 2017
Cerebrovascular
By: 
Stephen Grupke, MD
Source: 
JAMA

Saver et al. analyzed pooled data of 1,287 patients from five large randomized phase 3 trials evaluating the use of mechanical thrombectomy vs medical management in the emergent treatment of acute ischemic stroke secondary to large vessel occlusion (MR CLEAN,...

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Effect of Anesthesia on Outcomes of Endovascular Thrombectomy: A Randomized Clinical Trial

February 1, 2017
General Neurosurgery / Other
By: 
Michelle J. Smith, MD
Source: 
JAMA

Mechanical thrombectomy in select patients with acute ischemic stroke is a proven treatment. However, optimal anesthesia during this procedure is debated. Schonenberger et al. performed a prospective, randomized, blinded outcome trial assessing the use of general endotracheal anesthesia versus conscious...

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Endovascular thrombectomy after large-vessel ischemic stroke: a meta-analysis of individual patient data from five randomised trials

February 1, 2017
Cerebrovascular
By: 
Robert Starke, MD, MSc
Source: 
Lancet

 In 2015, five randomized trials showed efficacy of endovascular thrombectomy over medical care in patients with acute ischemic stroke caused by large vessel occlusion (LVO) of arteries of the proximal anterior circulation. A recent publication in the Lancet from the trial investigators from these trials, reported the pooled patient analysis of these studies...

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RESCUEicp Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension

January 10, 2017
Trauma / NeuroCritical Care
By: 
Roand Torres, MD
Source: 
New Eng J Med

Hutchinson et al. recently reported on the Randomised Evaluation of Surgery with Craniectomy for Uncontrollable Elevation of Intracranial Pressure (RESCUEicp) trial, comparing unilateral or bilateral decompressive craniectomy with...

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Guidelines for Severe Traumatic Brain Injury: 4th edition

January 10, 2017
Trauma / NeuroCritical Care
By: 
Roand Torres, MD
Source: 
Neurosurgery

Approximately 2.5 million Americans annually suffer traumatic brain injury (TBI). Severe TBI causes more than 30 percent of all injury-related deaths in the U.S. and account for 90 percent of the nearly $80 billion in annual costs. The new Guidelines...

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