Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Madison, Wisconsin
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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CV

Guidelines for Post-thrombectomy Management of ELVO Patients

December 4, 2017
Cerebrovascular
By: 
Michelle J. Smith, MD
Source: 
NCBI

Patients with emergent large vessel occlusions (ELVO) benefit from mechanical thrombectomy and appropriate postoperative care is necessary to optimize outcomes.  Recent SNIS guidelines covered post-thrombectomy care, ischemic penumbra, therapeutic hypertension, complication management, malignant cerebral edema, access site complications, and rehabilitation. ...

CV

DAWN Trial: Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

December 4, 2017
Cerebrovascular
By: 
Andrew W. Grande, MD
Shailesh Male, MD
Source: 
NEJM

In 2015, five major randomized controlled trials showed that thrombectomy for anterior large vessel ischemic strokes within 6 hours provided benefit. What about patients who present beyond 6 hours? The DAWN a multicenter, prospective, randomized, open-label, blinded endpoint trial was...

PE

ETV & Repeat ETV in Children

December 4, 2017
Pediatrics
By: 
Brandon G. Rocque, MD, MS
Source: 
J Neurosurg Pediatr

Breimer et al. report on the results of a large retrospective series of endoscopic third ventriculostomy (ETV) and repeat ETV, with the goal of analyzing the risk of repeat ETV failure compared to primary ETV, based on 624 ETV and...

SF

Better Quality of Life and Communication Outcomes After Asleep vs. Awake Placement of Deep Brain Stimulator

December 4, 2017
Stereotactic & Functional
By: 
Ellen L. Air, MD, PhD
Source: 
Neurology

In this study, 39 patients underwent standard subthalamic nucelus or globus pallidus pars interna DBS targeting via an awake surgery with micro-electrode recording (historical cohort). Another 30 patients underwent DBS under general anesthesia, guided by intra-operative CT fused to pre-operative...

CV

Endovascular Contact Aspiration vs Stent Retriever on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel Occlusion: The ASTER Randomized Clinical Trial

September 28, 2017
Cerebrovascular
By: 
Stephen Grupke, MD
Source: 
JAMA

This randomized, multicenter, open-label, blinded endpoint trial examines 381 patients with emergent M1 or M2 middle cerebral artery occlusions across 8 comprehensive stroke centers in France.  Eligible patients were randomized to undergo thrombectomy via stent retriever or contact aspiration with...

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