Neurosurgery Watch

Stay up to date with the latest clinical findings in Neurosurgery Watch. Each month, our panel identifies and summarizes key points of selected significant papers from over 50 journals. We emphasize the most significant findings that potentially change clinical management or treatment of neurological diseases.

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John S. Kuo, MD PhD FACS
Austin, Texas
Co-Editor
Robert Starke, MD MSc
Miami, Florida 
Co-Editor
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Hypothermia After Traumatic Brain Injury

December 10, 2018
Trauma
By: 
Erik Tarula MD
Source: 
JAMA

The hypothesis that hypothermia can improve functional outcome in traumatic brain injury has had several clinical failures, despite ample convincing animal data. The POLAR trial is an international, multicenter, randomized trial, examining the effects of early, sustained prophylactic hypothermia in...

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CDC Guidelines for Managing Pediatric Mild Traumatic Brain Injury

November 1, 2018
Pediatrics, Trauma
By: 
Brandon G. Rocque, MD MS
Source: 
CDC Guidelines

The US Centers for Disease Control and Prevention conducted a systematic review and published guidelines for Mild traumatic brain injury (mTBI) care, including 25 yrs of literature up to 2015. Nineteen sets of recommendations regarding imaging, diagnosis, risk factors, and...

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Complications following pediatric cranioplasty after decompressive craniectomy: a multicenter retrospective study

November 1, 2018
Pediatrics
By: 
Raheel Ahmed, MD, PhD
Source: 
Journal of Neurosurgery: Pediatrics

Renewed focus on neurosurgical health care quality metrics dictates critical evaluation of current practices and their impact on postoperative complications, hospital costs and patient outcomes. Cranioplasty procedures in both adult and pediatric patients have been traditionally been associated with significant...

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Clinical trial of dual immunotherapy agents for melanoma brain metastase

September 10, 2018
Tumor
By: 
Matthew Hunt, MD.
Source: 
NJEM

The study by Tawbi et al. published in the New England Journal of Medicine in late August examines the effects of dual-agent immunotherapy on intracranial metastatic disease. This open-label Phase II trial uses nivolumab and ipilimumab to treat patients with...

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Comparison of General Anesthesia vs. Conscious Sedation during Endovascular Therapy on Infarct Growth and Clinical Outcomes in Acute Ischemic Stroke

August 2, 2018
Cerebrovascular
By: 
Stephen Grupke, MD
Source: 
Neurosurgery

Previous studies have yielded conflicting results regarding patient outcomes after endovascular therapy for acute ischemic stroke depending on whether general anesthesia (GA) or conscious sedation (CS) was administered. The GOLIATH trial (General or Local Anesthesia in Intra Arterial Therapy) is...

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