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  • 30-Day Postoperative Outcomes Following Anterior Lumbar Interbody Fusion Using The National Surgical Quality Improvement Program Database

    Final Number:

    Nicholas B. Abt BS; Brandon A. McCutcheon MD MPP; Israel O. Olorundare; Panagiotis Kerezoudis; Meghan Murphy MD; Patrick R. Maloney MD; Ross Puffer MD; Mohamad Bydon MD

    Study Design:

    Subject Category:

    Meeting: Section on Disorders of the Spine and Peripheral Nerves 2016 Annual Meeting

    Introduction: Anterior lumbar interbody fusion (ALIF) is a common procedure used to treat various lumbar degenerative pathologies. The purpose of this study is to describe 30-day postoperative outcomes following ALIF on a national scale.

    Methods: The American College of Surgeons National Surgery Quality Improvement Program (ACS NSQIP) was searched for ALIF patients between 2005 and 2011. The top preoperative diagnoses were determined using ICD-9 codes. All available 30-day complications were grouped as overall composite morbidity and were compared between preoperative diagnosis groups by univariable and multivariable analyses.

    Results: There were a total of 1,352 ALIF patients. Overall, 6.73% of patients experienced a postoperative complication. Unplanned reoperations (2.48%), urinary tract infection (1.55%), superficial surgical site infection (1.41%), and sepsis (1.11%) were the most common morbidity events. The morbidity rates for each sub-group were: intervertebral disc degeneration (4.41%), spondylosis (6.72%), lumbosacral spinal stenosis (8.21%), and spondylolisthesis (8.41%). After extensive adjustment for patient characteristics and preoperative morbidities, multivariate analysis revealed spondylolisthesis (OR=3.29; 95% CI:1.04–10.46) and spinal stenosis (OR=3.76; 95% CI:1.33–10.63) to be associated with significantly higher overall morbidity odds when compared with lumbar disc degeneration, the diagnosis with the lowest overall morbidity. Lumbosacral spondylosis had similar outcomes as degenerative disc disease (OR =1.70; 95% CI:0.48–6.06).

    Conclusions: Diverse postoperative complications need to be managed following ALIF. Patients with spondylolisthesis and spinal stenosis may carry increased 30-day postoperative morbidity profiles in ALIF when compared to those with degenerative disc disease. Our data, with the current literature, suggest spinal diseases associated with a major inflammatory component may have higher rates of surgical postoperative complications. Prospective studies are needed to better delineate the outcomes of ALIF procedures, particularly in the spondylolisthesis and spinal stenosis patient populations.

    Patient Care: 1. stratify patient risk preoperatively for postoperative complications 2. develop strategies for morbidity avoidance for patients with spondylolisthesis undergoing ALIF 3. A decrease of implant and vessel manipulation can lead to a lower rate of venous injury 4. Usage of lower cage heights can decrease subsidence risk

    Learning Objectives: -Patients with spondylolisthesis and spinal stenosis carry an increased 30-day postoperative morbidity profiles in ALIF compared to degenerative disc disease -Spinal diseases associated with a major inflammatory component may have higher rates of surgical postoperative complications -The complication that occurred with the greatest frequency was unplanned reoperation -National morbidity rate after ALIF is approximately seven percent


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