Introduction: Intracranial Meningiomas are the most common primary intracranial tumors. There are several treatment options available (observation, radiotherapy, surgery, and combination of surgery and radiotherapy) with different outcomes. Patient and tumor related factors affect the choice of treatment method as well as patient’s survival. Presented here is a population-based database survival analyses of patients with intracranial meningioma.

Methods: We surveyed the National Cancer Database (NCDB) for the years 2004–2015 to identify patients with a diagnosis of intracranial meningioma using the International Classification of Disease 9 code. We then performed survival analyses of the retrieved data.

Results: A total of 199,096 patients with a diagnosis of intracranial meningioma met the inclusion criteria, 73.3% were females, and 76.4% were Caucasian. Mean age was 61 years old and mean Karnofsky score was 74.5. 73.4% of patients had no comorbidities. Patients treated at community hospitals had increased mortality in comparison to academic institutions for all treatment modalities. Increasing age and the presence of comorbidities were associated with increased mortality. Female gender was associated with increased survival. Tumors > 3cm in size and WHO grade II or III tumors were associated with increased mortality.

Conclusions: There are a multitude of factors that affect survival of patients with intracranial meningioma. This study reports a population-based database survival analyses for patients with intracranial meningioma.

Patient Care: This research presents the results of survival analyses of patients with intracranial meningiomas treated different treatment modalities. The results can be used to further refine existing treatment paradigms.

Learning Objectives: • Advancing age and the presence of comorbidities are associated with increased mortality in patients with intracranial meningioma. • Meningiomas with large size and/or high WHO grade are associated with increased mortality. • Meningioma patients treated at community hospitals have increased mortality compared to those treated at academic institutions.

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