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  • Fossa Navicularis: Literature Review, Diagnosis and Management

    Final Number:
    649

    Authors:
    A. F. Alalade FRCS(SN) (1,4); G. Briganti (2); J. Mckenzie (4); M. Gandhi (3,4); D. Amato (4); B. Panizza (4); J. Bowman (4)

    Study Design:
    Other

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2018 Annual Meeting

    Introduction: The fossa navicularis is an anatomical skull base variant. It represents a bony notch in the skull base, thought to be very rare and benign until recently, when 3 separate cases of intracranial infection associated with this finding have been reported.

    Methods: We reviewed the scientific searches – PubMed Central, EMBASE, Google Scholar, Scopus database, Cochrane database and Science Research, using the key words: fossa navicularis; canalis basilaris medianus; and pharyngeal fossa. We identified the papers where these terms were used, and described the unique features and clinical importance of this distinctive skull base radiological finding.

    Results: Our literature search covered papers from the 19th century till modern day literature. The earlier authors described ‘fossa navicularis’ as a very rare skull base finding. However more recently, 3 cases have been reported with associated clival or intracranial infection. To the best of our knowledge, this will be the 4th case reported in the literature and the only one that has been surgically repaired via an endonasal endoscopic approach. We present a 9 year old female who had presented with prior recurrent episodes of meningitis and was diagnosed with fossa navicularis. This skull base morphological anomaly should be considered in the differential diagnoses for unexplained skull base infective pathology.

    Conclusions: Fossa navicularis is a notch-like defect seen in the clivus. It is an anatomic skull base variant previously described in the literature as very rare. The cases reported were all associated with intracranial infection. This skull base morphological anomaly should be considered in the differential diagnoses for unexplained skull base infective pathology.

    Patient Care: As high resolution CT and MRI becomes increasingly accessible, we propose that careful scrutiny of the skull base will be beneficial for determining the real incidence of this anatomic variant and will also aid prompt diagnosis of the aetiologic factor in relevant infective scenarios. Our review suggests that the incidence might be higher than previously reported.

    Learning Objectives: This will help to highlight the importance of diagnosing this skull base anatomical variant especially in the pediatric population, and prevent the possible clinical consequences.

    References: 1. Kunimatsu A, Kunimatsu N. (2017) Skull Base Tumors and Tumor-Like Lesions: A Pictorial Review. Pol J Radiol, 82, 398. 2. Beltramello A, Puppini G, El-Dalati G, Girelli M, Cerini R, Sbarbati A, Pacini P. (1998) Fossa navicularis magna. AJNR Am J Neuroradiol, 19(9), 1796-1798. 3. Syed AZ, Mupparapu M. (2016) Fossa navicularis magna detection on cone-beam computed tomography. Imaging Sci Dent, 46(1), 47-51. 4. Currarino G. (1998) Canalis basilaris medianus and related defects of the basiocciput. Am J Neuroradiol, 9(1), 208-211. 5. Perna G. (1906) Sul canale basilare mediano e sul significato della fossetta faringea dell'osso occipitale. Anat Anz, 28, 379-392 6. Prabhu SP, Zinkus T, Cheng AG, Rahbar R. (2009) Clival osteomyelitis resulting from spread of infection through the fossa navicularis magna in a child. Pediatr Radiol, 39(9):995-998. 7. McBratney-Owen B, Iseki S, Bamforth SD, Olsen BR, Morriss-Kay GM. (2008) Development and tissue origins of the mammalian cranial base. Dev Biol, 322(1):121-132. 8. Miyahara H, Matsunaga T. (1994) Tornwaldt’s disease. Acta Otolaryngol 114(sup517), 36-39. 9. Romiti G. (1881) Canale basilare mediano dell'osso occipitale. Verb Soc Tosc Sci Nat Pisa, 219 10. Cankal F, Ugur HC, Tekdemir I, Elhan A, Karahan T, Sevim A. (2004) Fossa navicularis: anatomic variation at the skull base. Clin Anat, 17(2), 118-122. 11. Sheikh S, Iwanaga J, Rostad S, Rustagi T, Oskouian RJ, Tubbs RS. (2017) The First Histological Analysis of the Tissues Lining the Fossa Navicularis: Insights to its Etiology. Cureus, 9(5). 12. Segal N, Atamne E, Shelef I, Zamir S, Landau D. (2013) Intracranial infection caused by spreading through the fossa navicularis magna - A case report and review of the literature. Int J Pediatr Otorhinolaryngol, 77(12), 1919-1921. 13. Benadjaoud Y, Klopp-Dutote N, Choquet M, Brunel E, Guiheneuf R, Page C. (2017) A case of acute clival osteomyelitis in a 7-year-old boy secondary to infection of a Thornwaldt cyst. Int J Pediatr Otorhinolaryngol, 95, 87-90.

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