Skip to main content
  • Development of A Miniaturized Robotic Platform for Stereotactic Neurosurgery: Experience with Stealth AutoGuide from the First Series of 133 Patients

    Final Number:

    Stefan Wolfsberger MD; Georgi Yuri Minchev MD; Gernot Kronreif; Georg Widhalm; Svenja Maschke; Alexander Micko MD; Engelbert Knosp MD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2018 Annual Meeting

    Introduction: Stereotactic interventions are among the most frequent procedures in cranial neurosurgery. To overcome the limitations of frame-based, frame-less, or free-hand techniques, robotic arms have been introduced. Limited by their commonly large form-factor, AutoGuide has been designed as a miniature robotic guidance system dedicated to cranial neurosurgery. The aim of this study is to present the feasibility and accuracy of the AutoGuide robotic guidance device in stereotactic neurosurgical procedures in the routine clinical setting as well as future development and applications.

    Methods: During the last 4 years we conducted an approved clinical trial to assess and optimize the feasibility, OR setup and accuracy of the robotic guidance platform. Altogether, 133 cases were performed with AutoGuide including tumor biopsies (n=100), intracranial catheter (n=10) and depth electrode placements (n=23 patients, n=138 electrodes).

    Results: Application of AutoGuide was feasible in all cases. During the course of this trial, AutoGuide device was optimized to a state that allows operation by a single surgeon in the sterile field. Trajectory alignment error was =0.1mm in all cases. For stereotactic biopsies, the median real target error was 1.5mm (range 0.2 - 5.1mm) at entry points and 1.6mm (range 0.0 - 3.9mm) at target points. In SEEG procedures, median real target error was 1.1mm (range 0.0 - 3.4mm) at entry points and 1.5mm (range 0.2 - 5.6mm) at target points. In all cases of catheter placement, a satisfactory functional catheter position was achieved. No adverse effects related to the application of the robotic device were encountered.

    Conclusions: Our single center results indicate that application of AutoGuide in stereotactic neurosurgical procedures is feasible and provides high procedural accuracy without adding operating time. Due to its small form-factor, the robotic device was found to seamlessly integrate into the routine operating workflow. Future developments are focused on endoscope, brain trocar, and DBS electrode positioning.

    Patient Care: Application of robotic guidance improves accuracy and thus safety of frameless stereotactic procedures in cranial neurosurgery. The presented robotic platform will be applicable to most frameless procedures due to its miniaturized form factor and safe OR time due to its seamless workflow integration.

    Learning Objectives: By the conclusion of this session, participants should be able to: 1) Describe the importance of robotic guidance for stereotactic procedures, 2) Discuss the pros and cons of different types of available robots, 3) Identify patient cases that will benefit from robot guided surgery.

    References: 1. Minchev G, Kronreif G, Martínez-Moreno M, Dorfer C, Micko A, Mert A, Kiesel B, Widhalm G, Knosp E, Wolfsberger S: A novel miniature robotic guidance device for stereotactic neurosurgical interventions: preliminary experience with the iSYS1 robot. J Neurosurg. 2017 Mar;126(3):985-996. 2. Dorfer C, Minchev G, Czech T, Stefanits H, Feucht M, Pataraia E, Baumgartner C, Kronreif G, Wolfsberger S: A novel miniature robotic device for frameless implantation of depth electrodes in refractory epilepsy. J Neurosurg. 2017 May;126(5):1622-1628.

We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy