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  • Bilateral Anterior Cerebral Artery Pipeline Embolization “H-pipe” for Anterior Communicating Artery-Region Aneurysms

    Final Number:
    1019

    Authors:
    Geoffrey P. Colby MD, PhD; Matthew T Bender MD; Jessica K. Campos MD; Bowen Jiang MD; David A. Zarrin BS; Robert W C Young; Chau D. Vo BA; Justin M. Caplan MD; Judy Huang MD; Rafael Jesus Tamargo MD; Li-Mei Lin MD; Alexander L. Coon MD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2018 Annual Meeting

    Introduction: Anterior communicating artery (ACoA) aneurysms account for a disproportionate share of SAH. Surgical approaches have high morbidity and recurrence after coiling is common. Early experiences with flow diversion are promising but ACoA aneurysms may continue to fill after unilateral anterior cerebral artery (ACA) Pipeline Embolization (PED).

    Methods: A prospectively-maintained database of cerebral aneurysm patients treated with PED was reviewed to identify patients with ACoA-region aneurysms.

    Results: A total of 80 PED were performed on patients with ACoA-region aneurysms, 53 true ACoA and 27 aneurysms eccentric to the A1-2 junction. Bilateral ACA PED was performed on 11 patients (10 ACoA, 1 A1-2) in a total of 23 procedures. The average age was 59 and 82% were male. The average aneurysm size was 6mm (range 2-25mm). Four patients had a history of SAH and six had prior treatments. There was one major complication (4% of procedures, 9% of patients). The major complication was a quaternarian male with recurrent, previously-ruptured 3mm ACoA aneurysm who after second-stage R ACA PED awoke with left lower extremity paresis. DSA showed stent thrombosis, refractory to intra-arterial Abciximab, balloon angioplasty was performed, the vessel ruptured, and the patient did not survive. There were no other complications. Follow-up DSA obtained at an average of 9 months after stage two was available in 70% (7/10) of cases and showed complete occlusion in 86% (6/7). One patient with persistent filling from the right side after H-pipe underwent repeat R ACA PED and continued to fill the aneurysm at 6-month DSA following this procedure.

    Conclusions: A minority of true ACoA aneurysms may continue to fill after unilateral ACA PED; contralateral ACA PED in an “H-pipe” configuration may be used to achieve complete occlusion.

    Patient Care: This will expand the treatment armamentarium for a cohort of aneurysms that is at significant risk of rupture, for which existing treatments have either high morbidity (microsurgical clipping) or recurrence rates (endovascular coiling)

    Learning Objectives: To understand the role, risks, and efficacy of bilateral ACA flow diverting stents for treatment of anterior communicating artery aneurysms

    References:

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