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  • Minimally-Invasive Lumbar Interbody Fusion With an Expandable Meshed Allograft Containment Device: Analysis of Subsidence With 12-Month Minimum Follow-Up

    Final Number:
    571

    Authors:
    John Paul George Kolcun BS; George M. Ghobrial MD; Kenneth Crandall; Ken Hsuan-Kan Chang MD; Giacomo Pacchiarotti MS; Michael Y. Wang MD, FACS

    Study Design:
    Other

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2018 Annual Meeting

    Introduction: A minimally-invasive allograft-filled expandable meshed-bag containment system can be used in the lumbar spine for interbody fusion. Although graft subsidence is a key factor in selecting any interbody device, subsidence rate has not yet been reported with this device.

    Methods: Consecutive adult patients that underwent 1- or 2-level interbody fusion with at least 1 year of radiographic follow-up were included in this study. Preoperative, postoperative, and final follow-up lumbar radiographs were analyzed to measure disc height at the anterior and posterior margins of the disc space, as well as the neuroforaminal height.

    Results: Forty-one patients were identified, with a mean age of 63.4 years (SD ±11.8). A total of 61 levels were treated, with successful fusion observed in 54 levels (88.5%). The mean radiographic follow-up was 24.3 months (SD ±11.2). The mean disc height pre- and postoperatively was 6.9mm (SD ±3.2) and 10.1mm (SD ±2.9, p < 0.001), respectively. The mean disc height at final follow-up was 8.3mm (SD ±2.4). Average disc height subsidence was 1.8mm (SD ±1.7). Overall, average disc height increased by a net 1.3mm (SD ±2.5, p < 0.001). The mean neuroforaminal height pre- and postoperatively was 18.0mm (SD ±3.3) and 20.7mm (SD ±3.6, p < 0.001), respectively. The mean neuroforaminal height at final follow-up was 19.2mm (SD ±3.4). Average neuroforaminal height subsidence was 1.3mm (SD ±3.4). Overall, average neuroforaminal height increased by a net 1.7mm (SD ±2.8, p = 0.004). No significant difference in subsidence was observed between 1- and 2-level surgeries.

    Conclusions: An expandable allograft containment system is a feasible alternative for lumbar interbody fusion. Due to its biologic and mechanical characteristics, the surgeon using such constructs should account for an anticipated average 18% loss of interbody height due to subsidence during the bony remodeling/fusion process.

    Patient Care: This session will provide spine surgeons with valuable insight into the feasibility and long-term function of a novel interbody device, widening the field of available tools for patients with lumbar degenerative disease.

    Learning Objectives: By the conclusion of this session, participants should be able to: A. Recognize indications for a novel expandable interbody device B. Anticipate graft subsidence with this device 3) Discuss these possibilities with patients

    References: 1. Isaacs RE, Sembrano JN, Tohmeh AG, Group SDS. Two-Year Comparative Outcomes of MIS Lateral and MIS Transforaminal Interbody Fusion in the Treatment of Degenerative Spondylolisthesis: Part II: Radiographic Findings. Spine (Phila Pa 1976). 2016;41 Suppl 8:S133-144. 2. Kim CW, Doerr TM, Luna IY, et al. Minimally Invasive Transforaminal Lumbar Interbody Fusion Using Expandable Technology: A Clinical and Radiographic Analysis of 50 Patients. World neurosurgery. 2016;90:228-235.

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