• Co-existent Post-Herpetic Neuralgia and Trigeminal Neuralgia: Complete Resolution following Microvascular Decompression

    Final Number:

    Sheela Vivekanandan MD; Raghuram Sampath MD

    Study Design:

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2018 Annual Meeting - Late Breaking Science

    Introduction: Post Herpetic Neuralgia (PHN) is distinct from Trigeminal Neuralgia (TN) pain. Co-existence of the two pain types results in immeasurable psychosocial morbidity. PHN is usually self-limiting and conservatively managed. Medically refractory TN with a vascular loop is treated with microvascular decompression (MVD). We discuss a patient with PHN and TN (with vessel contact at REZ on MRI) treated with MVD with complete pain resolution.

    Methods: 48-year-old female with a 12-year history of left facial pain that started after a bout of zoster. She described a baseline constant burning pain; and a second type of sharp pain exacerbated by touch, face washing, brushing teeth – Type I TN. She had failed Lyrica, gabapentin, lidocaine patches and nerve block injections. FIESTA MRI demonstrated a vascular loop contacting the left trigeminal nerve REZ.

    Results: Based on MR imaging and a despondent patient with symptoms for 12 years, MVD was performed keeping in mind symptom relief could be partial at best. Dense arachnoid scarring with matted arteries and veins was noted. After careful scar tissue resection around the trigeminal nerve, a small SCA was found and mobilized along with placement of Teflon pledgets. In addition two veins adhered to the nerve were also noted and these were coagulated and cut. On post operative day two she reported complete relief of both PHN and Type I facial pain. At 1 month follow up she continues to be symptom free with intact facial sensation.

    Conclusions: Patients with co-existing PHN and Type I TN pain could be offered MVD if MRI demonstrates a vascular loop. Perhaps scar tissue and venous compression may have an etiopathogeneic role in PHN pain and a surgical role in management of this pain type needs be incorporated in our treatment strategy.

    Patient Care: Introduce a novel approach to patients with post-herpetic neuralgia, and to report a unique case of concomitant post-herpetic neuralgia and trigeminal neuralgia.

    Learning Objectives: 1. Inflammation and scar tissue along with venous compression may have role in origin of PHN pain. 2. MVD might need to be included as an important treatment option in medically refractory PHN pain; irrespective of if type 1 TN pain is present or not; with or without a vessel loop around REZ of trigeminal nereve. 3. Define how to differentiate type 1 trigeminal neuralgia pain from post herpetic neuralgia.

    References: Feller L, Khammissa RAG, Fourie J, et al. Postherpetic neuralgia and trigeminal neuralgia. Pain Res Treat. 2017 Green AL, Nandi D, et al. Post-herpetic trigeminal neuralgia treated with deep brain stimulation. J Clin Neurosci. 2003. Johnson MD, Burchiel KJ. Peripheral stimulation for treatment of trigeminal post herpetic neuralgia and trigeminal posttraumatic neuropathic pain: a pilot study. Neurosurgery. 2004 Mason A, Ayres K et al. A Novel Case of Resolved Postherpetic Neuralgia with Subsequent Development of Trigeminal Neuralgia: A Case Report and Review of the Literatur. Case Rep Med. 2013.

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