Skip to main content
  • Operative Approaches for Lumbar Disc Herniation: A Systematic Review and Multiple Treatment Meta-analysis of Conventional and Minimally Invasive Surgeries

    Final Number:

    Mohammed Ali Alvi M.D.; Panagiotis Kerezoudis MD; Jenna Meyer; Sandy Goncalves MSc; Brett Arthur Freedman; Mohamad Bydon MD

    Study Design:

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2017 Annual Meeting

    Introduction: Open discectomy (OD) and micro-discectomy (MD) are considered the gold-standard surgical approach for lumbar disc herniation. During the last 2 decades, minimally invasive surgery (MIS) techniques have emerged as viable and safe alternatives, including percutaneous (PD), percutaneous endoscopic (PED) and tubular discectomy (TD).

    Methods: We conducted a systematic review and multiple treatment meta-analysis of the available literature using the PRISMA guidelines. The techniques were compared with regards to patient-reported outcomes including Oswestry Disability Index (ODI) and Visual Analogue Scale (VAS), surgical outcomes and complications.

    Results: 1707 patients (14 studies) were analyzed, with 782 (45.81%) undergoing OD/MD, 491 (28.76%) undergoing TD, 235 (13.76%) patients undergoing PD and 199 (11.65%) undergoing PED. OD/MD was found to be associated with significantly longer duration of stay (MD 2.96, p=0.04), more blood loss (MD 30.53, p= <0.001), worse ODI scores at last follow-up (2-5 years) (MD 2.61, p= 0.03) and less revision-surgery (OR 0.53, p<0.001). On the other hand, TD was found to be associated with better ODI score at last follow-up when compared to MD/OD (MD -1.70, p=0.005). TD was also found to have higher rate of overall complications (OR 1.49, p= 0.002), dural tears (OR 1.72 p=0.04) and recurrent disc-herniation (OR 2.09, p <0.001) when compared to all others. Finally, PED was found to have significantly less complications when compared to MD/OD (OR 1.62, p=0.04) and TD(OR 2.05, p=0.006) as well as less dural tears compared to all approaches (OR 0.28, p= 0.04). Our analysis could not detect any difference in VAS leg pain and VAS back pain scores among all approaches.

    Conclusions: Our analysis revealed that while MD/OD is associated with less complications like dural tears and recurrent herniations, MIS techniques have superior long-term ODI-scores at last follow up as well as significantly less length of stay and blood loss.

    Patient Care: Our study provides clarity about each of the surgical techniques employed to treat lumbar disc herniation. We also identified advantages and pitfalls of each of the techniques. At the end of the day, meta-analysis rely on the quality of the included studies. A well-designed randomized controlled trial is required to validate the analysis of our study.

    Learning Objectives: MIS techniques yield significantly better ODI score at last follow-up, when compared to MD/OD. OD/MD is associated with longer duration of stay and more blood loss. TD is associated with higher overall complications, higher incidental dural tears and recurrent herniations. PED yields lower overall complications, lower incidental dural tears and lower recurrent herniation.


We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy