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  • Extraforaminal Lumbar Disk Herniation: Open versus Minimally Invasive Surgery A Systematic Review and Meta-analysis

    Final Number:

    Oluwaseun Akinduro M.D.; Panagiotis Kerezoudis MD; Jang W Yoon MD. MS. BS.; Mohammed Ali Alvi MD; Sandy Goncalves MSc; Jenna Meyer; Selby G. Chen MD; Mohamad Bydon MD

    Study Design:

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2017 Annual Meeting

    Introduction: Far lateral disk herniation accounts for 3-11% of all disk herniations. Despite the heterogeneity of spinal procedures, there is a paucity of literature comparing the outcomes from different surgical approaches.

    Methods: We performed a systematic review and meta-analysis of all publications, examining literature available for extraforaminal disk herniations. Articles were limited to full text articles involving humans published in English, which resulted in 205 articles that were reviewed for inclusion. We excluded studies with less than 8 patients, thoracic disk herniation, imaging studies, cadaveric studies, articles in which the extraforaminal patients were not analyzed separately, and articles with only paramedian or intraforaminal herniation patients.

    Results: The minimally invasive (MIS) group (tubular microscopic, percutaneous endoscopic & micro-endoscopic) showed no significant difference from open surgical (OS) group in the incidence of complications (OS: 0.01, MIS: 0.01; p=0.971) or re-operation (OS: 0.04, MIS: 0.03; p=0.382). There was an increased incidence of poor MacNab criteria outcomes for the OS group compared to the MIS group, but the difference was not statistically significant (OS: 0.14, MIS: 0.06; p=0.237). The OS group had higher estimated blood loss (WMD: 38.6 mL), longer operative time (WMD: 12.2 minutes), longer hospital stay (WMD: 30.3hours), and longer return to work time (WMD: 3.3 weeks). Tubular microscopic studies had lower incidence of re-operation than both percutaneous endoscopic (PED: 0.06, TM: 0.01; p=0.01) and micro-endoscopic (ME: 0.05, TM: 0.01; p=0.03).

    Conclusions: Our study found that MIS procedures for extraforaminal disk herniations are associated with a similar incidence of complications and re-operation but lower EBL, shorter operative time, longer hospital stay, and longer return to work time. Tubular microscopic procedures have the lowest re-operation rate of MIS procedures and micro-endoscopic procedures had the longest operative time. Spine surgeons should be aware of potential differences in patient outcomes when selecting one technique vs. others.

    Patient Care: By highlighting the surgical outcomes profile associated with each surgical technique for the treatment of far lateral disc hernations

    Learning Objectives: The authors should be discuss the different surgical techniques available for the treatment of far lateral disc herniations and describe the short- and long- term outcomes associated with each.


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