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  • Pediatric Meningiomas. A Retrospective Analysis of 37 Surgical Cases.

    Final Number:
    655

    Authors:
    Dattatraya P. Muzumdar; sonal Ashok jain MBBS MS MCh; Atul H Goel MD

    Study Design:
    Other

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2017 Annual Meeting

    Introduction: Background: Pediatric meningiomas are infrequently encountered in clinical practice. In comparison to adults, they have a distinct pathophysiology and clinical presentation. They are benign but locally aggressive tumors. Radical excision often culminates in good outcome.

    Methods: The case records of patients less than 18 yrs of age operated for meningiomas in our institute from 1985 to 2014 wasretrieved. The demographic profile, clinical and radiological features, surgical approach, extension of resection and surgical outcome were recorded and subsequently analyzed.

    Results: Results: Amongst 37 patients, 20 were males and 17 were females. The mean age was 13 years. 20% children had identifiable predisposing etiologies like Neurofibromatosis and radiation exposure. There were 31 intracranial and 6 spinal meningiomas. Headache associated with vomiting was the most presenting complaint. Majority were supratentorial tumors. A safe maximal excision was attempted in each case.Recurrence was noted in 5 patients. Average follow-up was about 24 months.2 patients succumbed to their illness and 30% patients had significant morbidity.

    Conclusions: Although rare, pediatric meningiomas are biologically different from their adult counterparts. They have a male predominance, common in intraventricularregion and cystic in nature. Radical excision is associated with good prognosis. Although benign, they are aggressive in nature and have a tendency to recur.The response to adjuvant therapy is modest. Further molecular research and genetic studies are necessary to understand the biology of pediatric meningiomas, which will help in indentification of targeted molecular therapy.

    Patient Care: Our study confirms that pediatric meningiomas are different from adults in many aspects and hence require customized management accordingly.They are aggressive and have high tendency to recur.Benefits of adjuvant treatment are modest and hence our study helps to emphasize the fact that maximal safe excision should be attempted in every patient.

    Learning Objectives: To study the demographic profile, clinicoradiological features, pathophysiology and surgical outcome of childhood meningiomas.

    References:

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