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  • Utility of Microwave Ablation in Brain Tumor Surgery: Preliminary Report of Fifteen Cases

    Final Number:

    Adrian Santana Ramirez MD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2016 Annual Meeting

    Introduction: rain tumor surgery requires good planning and specific tools such ultrasonic aspirator, bipolar, microsurgical instruments. The use of new tools or equipment to enable better outcomes and improves quality of life is mandatory. Microwave Ablation (MW) is a technique used from other field since 2005 in liver,tiroid tumor with good results. With imaging guidance, the tumor is localized, and a thin (14.5gauge) microwave antenna is placed directly into the tumor. A microwave generator emits an electromagnetic wave through the exposed, noninsulated portion of the antenna.(1).

    Methods: Fifteen cases are described with Brain tumors ,four Astrocytoms and four Glioblastoma Multiforme(GBM).One Cordoma and One Metatstais,and Five malignant Meningiomas Treated with Microwave Ablation during convencional surgery. All cases the tumor was localized with image guidance by using Transoperative Ultrasound Aloka 5500. A thin (14.5gauge)antenna .(MEDWAVES ) and energy was applied for 1- 3 minutes until the temperature sensor at proximal position of the 4-cm antenna reached 7090°Celcius The cortical brain surface temperature registered 32 to 34 degrees Celsius during the ablation process. Cavitation and ablation was observed, and adjacent vascular and brain structures were preserved, visualized by surgical microscope and Doppler ultrasound Transoperative. Histopathological results of Astrocytoms and Glioblastoma Multiforme,Cordoma,and metastais were confirmed

    Results: The Aplication of MW Ablation Intratumoral during Brain surgery was Safe, in All Cases no aditional neurological deficit was detected. The Brain temperature arroud of the tumor was 32 to 34 Celsius grades. The intratumoral vascular flow was decreased,and the tumor was more easy removed.Four cases was treayed only with Microwave Ablations with good outcomes.

    Conclusions: 1.-Microwave Ablation is excellent tool for BrainTumors Surgery 2- Was safe in all cases 3.-Decrease Intratumoral Blood Flow , Therefore enable the microsurgical resection. 4.-The only use of microwave in brain surgery seem to be effective in the treatment of brain tumors 5.-The Life expectancy of High Grade of Gliomas was more 15 months, and Karnofsky score was more more 80 the first 12 months

    Patient Care: a)New tool for treating brain tumors b)Possible dual microwave effect: heat microwave and belatedly effect on tumor b)

    Learning Objectives: The participants should be able to understand the new aplication tehcnique for of the Brain Tumor surgery

    References: 1. Microwave ablation: principles and aplications Simon CJ1, Dupuy DE,Mayo-smith ww Radiographics 2005 oct:25 Suppl 1:S6983 2.-Microwave Tissue Ablation: Biuophysics, Technology and Applications Christopher L. Brace, PhD Crit Rev Biomed Eng 2010, 38(1) 65-78

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