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  • Analysis of Thin-walled Regions in Unruptured Cerebral Aneurysms Using Computational Fluid Dynamics

    Final Number:

    Emiko Hori MD; Kimiko Umemura Oya; Soshi Okamoto; Michiya Kubo; Satoshi Hori; Takashi Shibata; Yukio Horie; Daina Kashiwazaki; Naoki Akioka; Naoya Kuwayama; Satoshi Kuroda MD PhD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2016 Annual Meeting

    Introduction: During the neck clipping of cerebral aneurysm, the abruption of normal vessels from aneurysm might be needed. The aim of this study was to evaluate the relationship between thin-walled regions of unruptured cerebral aneurysms and hemodynamic factors, and the thin-walled regions are able to predict or not before surgery.

    Methods: Computational fluid dynamics (CFD) analysis was performed 49 aneurysms in 47 patients based on angiography, 3 dimensional-computed tomography or magnetic resonance angiography. Pressure, Wall shear stress (WSS) were evaluated at the 60 point of thin-walled regions defined as red wall from intraoperative findings. % Flow rate and volume of aneurysms also evaluated. % Flow rate calculated the flow rate of aneurysm divided the flow rate of parent artery. % Flow rate was compared the thin-walled points that have a translucency (n=13) to the others (n=36).

    Results: Above 80% points of thin-wall regions revealed high pressure, but, there was no tendency of WSS. % Flow rate correlated with volume of aneurysms excluded 2 large one. % Flow rate was high at the thin-walled points that have a translucency (72.7±34.8 VS 52.6±34.8).

    Conclusions: These results showed that the place of high pressure tended to thin-walled points, especially have the translucency. CFD analysis might be helpful for prediction of thin-walled points of unruptured cerebral aneurysms.

    Patient Care: For the safety of doing operation of unruptured cerebral aneurysms, there are many tools. Computed fluid dynamics analysis might be one of them to evaluate the this-walled regions.

    Learning Objectives: By the conclusion of this session, participants should be able to evaluate the relationship between thin-walled regions of unruptured cerebral aneurysms and hemodynamic factors.


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