In gratitude of the loyal support of our members, the CNS is offering complimentary 2021 Annual Meeting registration to all members! Learn more.

  • Does Base Deficit Predict Mortality in Patients With Severe Traumatic Brain Injury?

    Final Number:
    1392

    Authors:
    mubbashira hussain siddiqui MBBS; Muhammad Waqas MBBS

    Study Design:
    Other

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2016 Annual Meeting

    Introduction: Base Deficit (BD) is a marker of tissue hypoxia in polytrauma patients. It guides resuscitative measures, and predicts outcomes, complications and mortality. The aim of this study was to examine the presence of BD in patients with isolated severe traumatic brain injury (TBI), and to assess if it correlates with the outcomes in these patients

    Methods: This was a retrospective observational study. All patients over the age of 16 years presenting to Aga Khan University Hospital from 2009 to 2013 with isolated TBI, were included. Data was extracted from 2009 to 2013. Glasgow Outcome Scale (GOS) of 4 and 5 at last follow up was categorized as favorable outcome. Data was analyzed using SPSS version 19 and receiver operative curve (ROC) was generated for BD as a predictor of mortality and unfavorable outcome

    Results: One hundred and eight patients were analyzed. Ninety-eight (90.7%) were males. Mean age was 36.69 ± 17.65. Eighty-eight (81.5%) patients had BD, while 20 (18.5%) patients had base excess. 62 (58.5%) of the patients had unfavorable outcomes. BD on admission had a statistically significant negative correlation with Glasgow Coma Scale (GCS) on presentation (r = -0.239, p = 0.025) and Revised Trauma Score (RTS) (r = -0.214, p = 0.046). However, there was no statistically significant difference in means of BD between survivors and non survivors. Area under receiver operator curve (ROC) for BD as a predictor of mortality statistically non-significant

    Conclusions: Although BD is correlated with GCS at presentation and RTS, it is not a reliable prognostic marker for outcome and mortality in patients with isolated TBI.

    Patient Care: it will help in understanding of brain injuries in trauma patients

    Learning Objectives: BD has not been evaluated as a prognostic indicator in patients with isolated head injury. • Study is a critical analysis of 108 patients with severe head injury and base deficit. • BD on admission had a statistically significant negative correlation with Glasgow Coma Scale (GCS) on presentation (r = -0.239, p = 0.025) and Revised Trauma Score (RTS) (r = -0.214, p = 0.046). • There was no statistically significant difference in means of BD between survivors and non survivors. • Area under receiver operator curve (ROC) for BD as a predictor of mortality statistically non-significant

    References:

We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy