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  • Posterolateral Lumbar Fusion: Relationship Between CT Hounsfield Units and Symptomatic Pseudoarthrosis

    Final Number:

    Ha Nguyen MD; Saman Shabani BS, MD; Mohit Patel; Dennis J. Maiman MD

    Study Design:

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2016 Annual Meeting

    Introduction: Assessment of bone quality can guide spinal surgery. However, surgeons infrequently evaluate bone quality in a quantitative manner. Recent literature suggests a role for CT Hounsfield Units (HU) as a marker for bone quality. Limited data exist regarding its utility with respect to posterolateral lumbar fusion (PLF).

    Methods: From Fall 2010 to Winter 2012, ten patients underwent revision surgery for symptomatic pseudoarthrosis (defined as intractable pain associated with either radiographic evidence of nonunion or intraoperative evidence of nonunion) after a prior L4-S1 PLF. These patients were age-matched (+/-5 years) to ten patients who underwent L4-S1 PLF with no clinical signs of pseudoarthrosis at 1-year follow-up. Available CT imaging (with or without instrumentation) was evaluated from L1 to L5 for the averaged HU. Data were pooled among L1-L2-L3 values and between L4-L5 values.

    Results: Within the pseudoarthrosis group, the pooled L1-L3 HU value was similar to the pooled L4-L5 HU value (168.39+/-22.84 HU versus 166.98+/-23.20 HU respectively, p = 0.89). The same pattern was observed for the control group (190.24+/-37.13 HU versus 201.89+/-36.59 HU respectively, p = 0.44). On the other hand, the pooled L1-L3 and L4-L5 HU values were larger for the control group compared to the pseudoarthrosis group, with the pooled L4-L5 HU demonstrating statistical significance, p = 0.01.

    Conclusions: Currently, CT imaging is typically not obtained prior to lumbar fusion. Results demonstrated that CT HU values were significantly larger for patients who did not exhibit symptomatic pseudoarthrosis at one-year follow-up compared to those who required revision surgery. As such, CT HU values may serve as a predictor for bony fusion to guide surgical management of patients under consideration for PLF.

    Patient Care: Discusses use of CT HU values as potential predictor for bone fusion, which helps clinical management of spinal fusion

    Learning Objectives: 1) Appreciate the potential role of CT HU values for the evaluation of bone quality 2) Appreciate the potential role of CT HU values for the assessment of bone fusion

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