Skip to main content
  • Frailty Index is a Significant Predictor of Complications and Mortality Following Adult Deformity Surgery (ADS)

    Final Number:

    Dante Leven DO; Parth Kothari BS; Javier Z Guzman BS; John I Shin BS; Jeremy Steinberger MD; Branko Skovrlj MD; Nathan John Lee BS; John M. Caridi MD; Samuel K Cho MD

    Study Design:

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2015 Annual Meeting

    Introduction: Modified frailty index (mFI) is a measure of health status in ageing individuals and is an important factor that can be used to predict morbidity and mortality. In adult deformity surgery (ADS), a higher mFI score could be associated with increased rates of complications and mortality.

    Methods: This was a retrospective analysis of prospectively collected data from the NSQIP database of patients > 18 years old undergoing ADS between 2005 and 2012. A previously described mFI was calculated based on number of positive factors out of 11 (see table 1). Complications and mortality were analyzed using univariate and multivariate logistic regression analysis with significance defined as p < 0.05. Odds ratio (OR) was calculated with a 95% confidence interval.

    Results: 4,793 patients were identified and the mean mFI was 0.07 (0-0.545). Increasing mFI score was associated with increased complications, mortality and morbidity (p<0.05). As the mFI score increased from 0.27 (3/11) - = 0.36 (4/11), mortality increased from 1.88% to 3.13% (p<0.0001, OR 5.849, 0.87-39, 95%CI), cardiac complications 5.16% to 7.81% (p<0.0001, OR 14.0, 3.10-63.2,95%CI), sepsis 0.94% to 6.25% (p<0.0001, OR 4.59,1.20-17.57,95%CI), UTI 3.29% to 7.81% (p<0.0001, OR 3.34, 1.12-9.65,95%CI), wound complications 4.23% to 9.38% (p<0.0001, OR 4.42, 1.57-12.5,95%CI) and pulmonary complications 0.47% to 1.56% (p<0.0001, OR 7.02, 2.61-18.874, 95%CI).

    Conclusions: Patients with higher mFI scores (= 4/11 variables) are at significantly increased risk of major complications, sepsis and death following ADS. These findings highlight the importance of careful patient selection and sound preoperative work-up.

    Patient Care: Understanding the significance of the mFI and its relationship to complications and mortality is critical for spine care providers to provide top-level patient care.

    Learning Objectives: By the conclusion of the session, participants should be able to analyze the mFI as a predictor for complications within 30 days following ADS.


We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy