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  • Does Putting Back Hyperostotic Bone Flap in Meningioma Operation Cause Tumor Recurrence? An Observational Study

    Final Number:
    435

    Authors:
    Bik Liang Lau; Swee San Lim MS; Donald Ngian San Liew FRACS; Albert Sii Hieng Wong FRACS

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2015 Annual Meeting

    Introduction: Replacing the skull defect with synthetic materials for hyperostotic bone secondary to meningioma operation is recommended due to the possibility of tumour invasion. In our center neurosurgeons are putting back the refashioned hyperostotic bone flap after meningioma excision due to budget constraint.

    Methods: This observational study was conducted from 2011 to 2014, with selected intracranial meningioma patient. Pre-operative computed tomography brain (CTB) scans were done in all patients and reviewed during the preoperative rounds to confirm bony hyperostosis. Intraoperatively part of the hyperostotic bone was sent for histopathological examination. The rest of the bone was refashioned by drilling off the hyperostotic part. The flap was put back over the craniotomy site after soaking in distilled water. All these patients were followed up in our neurosurgery clinic for any tumor recurrence.

    Results: This study included 16 patients with meningioma WHO grade I with Simpson I-II excision. Radiological evidence of hyperostosis was present in all patients. No recurrence was seen over a mean follow-up of 22 months (range 6-45 months). On histopathological examination, tumor invasion of the bone was seen in 8 (50%) patients. One of the patients needed to have the refashioned bone flap removed 1 year after operation due to infection.

    Conclusions: Autologous cranioplasty with refashioned hyperostotic bone in meningioma cases has not shown any tumor recurrence with a mean follow-up of 22 months. A larger number of patients with a longer duration of follow-up are needed in order to yield a more significant result.

    Patient Care: Through this study, we will be able to know the tumour recurrence surveillance by putting back refashioned hyperostotic bone flap in meningioma.

    Learning Objectives: Tumour recurrence surveillance using refashioned hyperostotic bone flap cranioplasty.

    References:

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