Skip to main content
  • Motor Evoked Potentials Predict Recovery in Spinal Cord Injury

    Final Number:

    Sanjay S. Dhall MD; Geoffrey T. Manley MD, PhD; Jason Talbott MD, PhD; Jonathan Pan MD, PhD; Michael Beattie PhD; Jacqueline Bresnahan PhD; William Whetstone MD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2015 Annual Meeting

    Introduction: Whilst the utilization of intraoperative neurophysiologic monitoring (IOM) with somatosensory (SSEP) and motor evoked potentials (MEP) has become widespread in spine surgery, scientific studies of its diagnostic and therapeutic benefit have been limited. This study aims to describe the IOM experience at a large level I trauma center and assess for prognostic capability of this technology.

    Methods: The neurosurgery REDCAP database at our Level 1 Trauma Center was queried for patients with acute cervical spinal cord injury who underwent surgery with IOM between 2007 and 2011, yielding 32 patients. In addition to demographic data, we assessed preoperative and postoperative spinal cord injury severity (AIS grade), surgical data, use of steroids, and hemodynamic data.

    Results: The mean age in this cohort of patients was approximately 56 (range 22-85 yrs) and AIS grades were A (n=10), B (n=5), C (n=6), D (n=11). All patients underwent surgical decompression and stabilization with intraoperative SSEPs and MEPs. In the group of severe SCI (AIS A, B, C) patients with elicitable MEPs, AIS improved by an average of 1.5 grades, as compared to the patients without elicitable MEP who improved by 0.7 grades (p=0.005).

    Conclusions: In patients with severe SCI (AIS A, B, C) presence of MEPs was found to predict neurologic improvement. This significant finding warrants future prospective study MEP as a prognostic tool in SCI.

    Patient Care: The use of motor evoked potentials can prognosticate and potentially influence the management of acute spinal cord injury

    Learning Objectives: 1. To discuss the role of MEPs in SCI 2. Use of MEPs to guide treatment and provide prognostic data


We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy