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  • Gamma Knife Radiosurgery for Olfactory Groove Meningiomas

    Final Number:

    Selcuk Peker MD; Meltem Yilmaz; Haluk Cem Cakaloglu; Meric Sengoz

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2015 Annual Meeting

    Introduction: Due to the size of the tomurs at the time of diagnosis, radiosurgery is rarely the primary treatment option for olfactory groove (OG) meningiomas. On the other hand anosmia is a common outcome after resection of OG meningiomas. In this study, the tumour control rates and the outcomes of with OG meningiomas who underwent Gamma Knife (GK) radiosurgery were evaluated.

    Methods: We retrospectively reviewed patients treated with GK for OG meningiomas at our institution between May 2006 and April 2014. The median age was 58 years old (range 25-73y). There were 14 males and 24 females. Nine patients underwent craniotomy before the date of GK treatment. Volume stage treatment was performed in two session to a patient because of the large tumour size. The median tumour volume was 4.6 cc (range 0.8-30.1 cc) and the median marginal dose was 12 Gy (range 10-15 Gy). Treatments before August 2012 were performed with Leksell Gamma Knife 4C unit and were delivered by Leksell Gamma Knife Perfexion thereafter.

    Results: The median follow-up time was 41.5 months (range 12-106 months). Tumor control was achieved for all patients (100%). None of the patients experienced permanent side effects. Only one patient had loss of olfactory function. Ten patients had postradiosurgical peritumoral edema which responded well to short course of steroid treatment.

    Conclusions: Radiosurgery is an effective and safe treatment for small OG meningiomas. Radiosurgery can be considered as an initial treatment option for patients with small olfactory groove meningiomas.

    Patient Care: By using this method the quality of life will be better for OG meningioma patients.

    Learning Objectives: By the conclusion of this session, participants should be able to 1) Describe the indications for OG meningioma radiosurgery 2) Describe the results of radio surgery


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