Skip to main content
  • Risk of Development of New Onset Post Operative Cervical Deformity (CD) in Thoracolumbar Adult Spinal Deformity (ASD) and Effect on Clinical Outcomes at 2 year follow up

    Final Number:

    Alex Soroceanu; Peter G Passias MD; Anthony Boniello; Justin K Scheer BS; Frank Schwab MD, PhD; Christopher I. Shaffrey MD, FACS; Han Jo Kim MD; Themistocles Protopsaltis MD; Gregory Mundis MD; Munish Gupta MD; Eric Klineberg MD; Virginie Lafage PhD; Justin S. Smith MD PhD; Christopher P. Ames MD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2014 Annual Meeting

    Introduction: A high prevalence of residual cervical deformity (CD) has been identified following surgical treatment of adult spinal deformity (ASD). Development of new onset CD is less understood and its clinical impact unclear. This study quantifies the incidence of CD after ASD surgery, identifies predictors of development, and determines the impact outcomes.

    Methods: Retrospective review of prospective multi-center database yielded 215 patients (pts) with complete 2yr follow-up and full length xrays including the cervical spine. CD was defined by: T1S-CL>20°, C2C7 SVA>40mm, or C2C7 kyphosis>10°. Univariate analysis was performed using t-tests or tests of proportion. Multivariate logistic regression was used to determine independent predictors of new CD. The impact of CD on Health Related Quality of Life (HRQL) and satisfaction was measured using repeated measures mixed models or logistic regression as appropriate, accounting for potential confounders.

    Results: 88/215 ASD pts did not have CD at baseline and 42 of them (47.7%) developed CD at 2 years postop. Univariate analysis revealed that pts who developed new cervical deformity in the post op period had a higher incidence of diabetes (14.29%vs2.17%,p=0.036) increased pre-op C2C7 SVA (p=0.04) and C2 slope (p=0.038) and smaller diameter rods used at surgery (p=0.0328). Independent predictors of new CD at 2yrs included: diabetes (OR 10.49, p=0.046) and increased pre-op TS-CL (OR 1.08/deg,p=0.027). Ending instrumentation below T4 was a negative predictor of CD (OR 0.31, p=0.019). Pts with and without CD experienced improvements in 2yr SF-36 (p=0.0001), ODI (p=0.0001) and SRS (p=0.0001). Rates and overall improvement were similar. CD was not associated with decreased satisfaction (p=0.28).

    Conclusions: 47.7% of pts without preop cervical deformity develop new postop cervical deformity after ASD surgery. Independent predictors of new onset CD at 2yrs include diabetes, higher preop TS-CL, and ending instrumentation above T4. Significant improvements in HRQL scores occurred despite the development of postoperative CD.

    Patient Care: The results of this study will improve patient care for patient education on the risk of postop cervical deformity and by alerting surgeons to the risk factors so that greater attention can be paid to these select patients

    Learning Objectives: By the conclusion of this session, participants should be able to: 1) identify the postop incidence of cervical deformity being 47.7% and 2) identify risk factors for postop new onset cervical deformity


We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy