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  • Long Term Outcomes Analysis for Glomus Jugulare Tumors Treated with Stereotactic Radiosurgery or Stereotactic Radiotherapy

    Final Number:
    1511

    Authors:
    Julio LB Pereira MD; Sergei Terterov MD; Elena I. Fomchenko PhD; Antonio DeSalles MD PhD; Alessandra A. Gorgulho MD; Tania B. Kaprealian; Michael T. Selch; Stephen Tenn; Isaac Yang MD

    Study Design:
    Other

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2013 Annual Meeting

    Introduction: The management of glomus jugulare tumors has evolved tremendously over the past several decades. As such, the overall optimal treatment strategies for this tumor are not yet fully elucidated.

    Methods: A retrospective chart analysis was performed for all patients who underwent stereotactic radiosurgery (SRS) or stereotactic radiotherapy (SRT), for glomus jugulare tumors at the UCLA Medical Center over the last 20 years. Tumor stability was reported.

    Results: Twelve patients met the inclusion criteria and were analyzed. 8 patients were treated with SRS receiving an average of 1280 cGy at the 90% isodose line, except one who received 1500 cGy at the 50% isodose line, in a single fraction. 4 patients were treated with SRT receiving an average of 4625 cGy at the 90% isodose line in an average of 25.8 fractions. All tumors remained stable in size or demonstrated regression at an average follow up of 4.4 years. No instances of tumor progression were observed in the SRS or SRT treatment groups at last follow up. Tumor regression was observed in 50% of SRT patients and 12.5% of SRS patients, however that difference was not statistically significant (P = 0.2). No radiation induced adverse effects were observed in the follow up period.

    Conclusions: Our data suggests that SRS and SRT may be good alternatives to endovascular embolization or microsurgical resection of glumus jugulare tumors, with an excellent tumor control rate and little morbidity after long-term follow-up.

    Patient Care: SRS and SRT may be good alternatives to endovascular embolization or microsurgical resection of glumus jugulare tumors

    Learning Objectives: optimal treatment strategies for glomus jugulare tumors

    References:

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