Skip to main content
  • Clinical significance of pyramidal signs in patients with cervical myelopathy

    Final Number:

    Hossam A. El-Noamany MD PhD

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2013 Annual Meeting

    Introduction: This retrospective case series was performed to study the relationship between prevalence of pyramidal signs and the severity of cervical myelopathy. The study is focusing on patients having increased signal intensity in T2-weighted magnetic resonance imaging.

    Methods: Forty six patients complaining of cervical spondylotic myelopathy with increased signal intensity in T2-weighted magnetic resonance imaging were included. The neurological finding of the patients was reviewed for pyramidal signs presence. The prevalence of each pyramidal sign is calculated and correlated to severity of cervical mylopathy. The motor function scores of the upper and lower extremities for cervical myelopathy set by the Japanese orthopaedic association (m-JOA) scores are used to assess severity of myelopathy.

    Results: The most prevalent signs were hyperreflexia (89.1%), Hoffmann reflex (80.4%), babiniski sign (56.5%), and ankle clonus (39.1%). Babiniski sign, ankle clonus, and Hoffmann reflex showed significant association with the lower m- JOA score.

    Conclusions: In patients with cervical myelopathy, hyperreflexia showed the highest sensitivity and the ankle clonus the lowest sensitivity. The prevalence of the pyramidal signs is correlated with increasing severity of myelopathy.

    Patient Care: 1. It allow doctors to early identify cervical myelopathy, so outcome can be improved. 2. Operating patients earlier, prevent serious complications.

    Learning Objectives: 1. To know the importance of detecting pyramidal signs in cervival myelopathy patients. 2. To identify the clinical significance of increased signal intensity in MRI in cervical myelopathic patients. 3. To know the correlation between pyramidal signs and the increased signal in MR images.


We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy