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  • Surgical treatment of osteoporotic spinal fractures with expandable pedicle screw fixation: a 2-year follow-up.

    Final Number:

    Roberto Gazzeri MD; Andrea Faiola MD; massimiliano neroni MD; Claudio Fiore

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2013 Annual Meeting

    Introduction: The incidence of screw loosening increases significantly in elderly patients with severe osteoporosis. We investigated the clinical efficacy of expandable pedicle screws, standard pedicle screws augmented with PMMA and standard pedicle screws after osteoporotic vertebral fractures.

    Methods: Fifty-six consecutive patients with posterior fusion using pedicle screws after osteoporotic vertebral fractures were included in the study. Patients were divided in three groups : those with posterior fusion with titanium expandable screws (Osseoscrew, Scient’x-Alphatec) (group E), those with standard pedicle screws augmented with PMMA (group C), and those without PMMA augmentation (group NC). Pre-operative DEXA BMD examination showed a mean T-score of -3.2. Patients were observed for a minimum of 24 months. Outcome measures included screw loosening, Visual Analogue Scale, Oswestry Disability Index, and complications.

    Results: With the exception of osteoporotic status, there were no significant differences in the baseline status between the three groups. Twenty-four months after surgery, the VAS and ODI were markedly improved in the E and C groups. There were no complications related to the PMMA in the cement group and to the expansion in the expandable screws group. At 12 and 24 months follow-up, there were no instances of screw loosening or pull-out, and the screw-bone interface was good in the E and C group. On plain radiographs and spinal CT, there were no signs of radiolucency around the pedicle screws (group E) while the incidence of clear zones around the screws in the NC group was higher. Dynamic x-rays, revealed non- motion of the screws and no movement between the fused vertebral segments in the E and C groups. Implant failure occurred in one patient of NC group.

    Conclusions: Expandable pedicle screws and reinforcement of screws with PMMA can decrease the risk of screw loosening and achieve better fixation strength and clinical results in osteoporotic spinal fusion.

    Patient Care: The research will improve patient care comparing and identifying the most appropriate surgical treatment for osteoporotic spinal fractures.

    Learning Objectives: By the conclusion of this session, participants should be able to describe the importance of the selection of the appropriate screw fixation system (expandable screw, screw augmented with cement, screw without cement)for the treatment of osteoporotic spinal fracture, and identify and choose the most appropriate fixation treatment in osteoporotic patients


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