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  • Clinical Improvement Through Nonoperative Treatment of Adult Spinal Deformity: Who Is Likely to Benefit?

    Final Number:
    1091

    Authors:
    caroline poorman; Kseniya Slobodyanyuk; Justin S. Smith MD PhD; Themistocles Protopsaltis MD; Richard A. Hostin MD; Shay Bess MD; Gregory Mundis MD; Frank Schwab MD, PhD; Virginie Lafage PhD; ISSG

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2013 Annual Meeting

    Introduction: While surgery has been shown on average to be superior to nonoperative treatment for significant adult spinal deformity (ASD), nonoperative care remains a good option for many patients. Our objective was to determine the outcome of ASD patients who elected for nonoperative care.

    Methods: Retrospective review of nonoperative branch of a multicenter prospective database of ASD patients. Only patients with baseline (BL) and 1yr SRS-22 and radiographic data were assessed. Changes in SRS-22 were evaluated by domain and expressed in number of minimal clinically important differences (MCIDs) gained/loss; BL and 1yr scores were compared to age- and gender-matched normative references (NR).

    Results: 189 patients (mean=53yo) met criteria. At BL, Pain was the domain with the largest offset from NR for 44% of patients, followed by Appearance (22%) and Activity (20%). Analysis of change in the Pain domain at follow-up revealed that 24% of patients gained (improvement) >1MCID and 14.2% lost >1MCID. Percentages with gain or loss for Activity were 20% and 24.9%, and for Appearance were 13.3% and 9.3%, respectively. Patients who gained >1MCID had more severe BL scores than those losing >1MCID (p<0.001), but had no significant differences in radiographic parameters. For each domain, BL scores had significant impact on final outcomes: 77%-85% of the patients within 1MCID of NR at BL had outcomes less than 1MCID of NR at 1yr; this dropped to 28-37% for patients greater than 1MCID of NR at BL, and 11% to 16% for those between 2-4MCID of NR at BL (p<0.001).

    Conclusions: Patients who received nonoperative care are more disabled than age- and gender-matched normative references. At 1yr, the likelihood to reach SRS scores similar to normative reference decreases with increased baseline disability. Nonoperative treatment is a viable option for certain ASD patients, and up to 24% demonstrated significant improvement over 1yr.

    Patient Care: Improve our understanding of non-operative treatment for adults with spinal deformity.

    Learning Objectives: By the conclusion of this session, participants should be able to: (1) Appreciate that, although surgery has been shown on average to be superior to nonoperative treatment for significant adult spinal deformity, nonoperative care remains a good option for many patients; (2) Appreciate that at 1 year follow-up, 24% of patients with adult spinal deformity treated with nonoperative measures demonstrated significant improvement.

    References:

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