Skip to main content
  • Predictors of Outcome in Gunshot Wounds to the Head

    Final Number:
    1002

    Authors:
    Bizhan Aarabi MD; Babak Towfighi; Jeffrey Hadley MD; Joseph Kufera MA; Edward Sanghoon Ahn MD; Kheder Ashker MD; Louis Chang MD; Carnell Cooper MD; Jacek M. Malik; Neal J. Naff MD; Michael Radley

    Study Design:
    Clinical Trial

    Subject Category:

    Meeting: Congress of Neurological Surgeons 2013 Annual Meeting

    Introduction: Civilian gunshot wounds to the head (GSWH) are deadly. Predictors of clinical outcome due to GSWH were analyzed over a 24-month period.

    Methods: We posited two questions: 1) What percentage of subjects with GSWH died across the state of Maryland; and 2) What were the predictors of good outcome (GOS) following GSWH? Demographics, clinical, imaging and acute care data of 786 civilians who sustained GSWH were analyzed. Univariate and regression analyses were used to analyze the data.

    Results: Of this cohort (N= 786 patients), 594 died at the scene and 122 died following admission to 8 Level I-III Trauma Centers. Seventy patients made it to TBI rehabilitation of which 30 (3.8%) had surgery. From the 69 patients who were admitted to this Level I Trauma Center, 78.6% were male, mean age was 34.8, injury severity score 26.7, GCS 7.1, and abnormal pupillary response to light (APR) was present in 47.4% of patients. CT scan indicated midline shift in 17.5%, obliteration of basal cisterns in 42.5%, intracranial hematomas in 35% and intraventricular hemorrhage in 55% of cases. Two subsets of admissions were studied: (1) 27 patients who died during acute care and (2) 15 patients who had a good outcome when followed a mean of 39 months. Missile trajectory (p< 0.001), admission GCS (p< 0.001), APR (p=0.002), patency of basal cisterns (p= 0.01), age (p= 0.02) and intraventricular bleed (p= 0.03) had significant relationship with outcome. Stepwise multivariable logistic regression analysis indicated that GCS and patency of basal cistern were significant determinants of outcome. Exclusion of GCS from the regression models indicated missile trajectory and APR were significant players in determining outcome.

    Conclusions: GCS at admission, APR to light, patency of basal cisterns and the trajectory of the missile were significant determinants of outcome in civilian GSWH.

    Patient Care: Better selection of patients for conservative or surgical intervention in order to have the best clinical outcome

    Learning Objectives: This investigation will empower neurosurgeons to better select victims of GSWH for the best possible outcome

    References: Aarabi B Alden TD, Chesnut RM et al. Management and Prognosis of Penetrating Brain Injury. J Trauma 51(Suppl), S1-S85. 2001. Aldrich EF, Eisenberg HM Saydjari C Foulkes MA Jane JA Marshall LF Young H Marmarou A. Predictors of mortality in severely head-injured patients with civilian gunshot sound: A report from the NIH Traumatic Coma Data Bank. Surgical Neurology 38, 418-423. 1992. Cavaliere R, Cavenago L et al. Gunshot wounds of the brain in civilians. Acta Neurochirurgica 94, 133-136. 1988. Clark CW, Muhlbaurer et al. Analysis of 76 civilian craniocerebral gunshot wounds. J Neurosurg 65, 9-14. 1986. Frankowski RF, an Lee RK. Epidemiology: Incidence and mortality of craniocerebral missile wounds. In Missile Wounds of the Head and Neck, VI, Aarabi B, and Kaufman HH (Eds), AANS Publication Office, Lebanon, New Hampshire. pp:17-33. 1999. Freytag E. Autopsy findings in head injuries from firearms. Arch Pathhol 76, 215-225. 1963. Grahm TW, Williams FC Jr Harrington T Spetzler RF. Civilian gunshot wounds to the head: a prospective study. Neurosurgery 27(5), 696-700. 1990. Helling TS, McNabney WK Whittaker CK Schultz CC Watkins M. The role of early surgical intervention in civilian gunshot wounds to the head. J Trauma 32, 398-400. 1992. Hernesniemi J. Penetrating craniocerebral gunshot wounds in civilians. Acta Neurochirurgica 49, 199-205. 1979. Hubschmann O, Shapiro K Baden M Shulman K. Craniocerebral gunshot injuries in civilian practice – Prognostic criteria and surgical management experience with 82 cases. J Trauma 19, 6-12. 1979. Izci Y, Kayali H, Daneyemez M, Koksel T, and and Cerrahoglu K. The clinical, radiological and surgical characteristics of supratentorial penetrating craniocerebral injuries: a retrospective clinical study. Tohoku J Exp Med 201, 39-46. 2003. Kaufman Hh. Civilian gunshot wounds to the head [current perspective]. Neurosurgery 32 (6), 962-964. 1993. Kaufman HH, Levy ML Stone JL Masri LS Lichtor T Lavine SD Fitzgerald LF Apuzzo ML. Patients with Glascow Coma Scale scores 3, 4, 5 after gunshot wounds to the brain. Neurosurg Clinics of North America 6, 701-714. 1995. Kaufman HH, Makela ME Lee KF Haid RW Jr Gildenberg PL. Gunshot wounds to the head: A perspective. Neurosurgery 18, 689-695. 1986. Kim KA, Wang MY McNatt SA Pinsky G Liu CY Giannotta SL Apuzzo ML. Vector analysis correlating bullet trajectory to outcome after civilian through-and-through gunshot wound to the head: using imaging cues to predict fatal outcome. Neurosurgery 57 (4), 737-747. 2005. Kim TW, Lee JK Moon KS Kwak HJ Joo SP Kim JH Kim SH. Penetrating gunshot injuries to the brain. J Trauma 62 (6), 1446-1451. 2007. Levy ML, Rezai A Masri LS Litofsky SN Giannotta SL Apuzzo ML Weiss MH. The significance of subarachnoid hemorrhage after penetrating craniocerebral injury: Correlations with angiography and outcome in civilian population. Neurosurgery 32, 532-540. 1993. Liebenberg WA, Demetriades AK, Hankins M, Hardwidge C, and Hartzenberg BH. Penetrating civilian craniocerebral gunshot wounds: a protocol of delayed surgery. Neurosurgery 57, 293-299. 2005. Lillard PL. Five years experience with penetrating craniocerebral gunshot wounds. Surgical Neurology 9, 79-83. 1978. Nagib MG, Rockswold GL Sherman RS Lagaard MW. Civilian gunshot wounds to the brain; Prognosis and management. Neurosurgery 18, 533-537. 1986. Polin RS, Shaffrey ME Phillips CD Germanson T Jane JA. Multivariate analysis and prediction of outcome following penetrating head injury. Neurosurg Clin N Am 6 (4), 689-699. 1995. Selden BS, Goodman JM Cordell W Rodman GH Jr Schnitzer PG. Outcome of self-inflicted gunshot wounds of the brain. Ann Emerg Med 17 (3), 247-253. 1988. Shaffrey ME, Polin RS Phillips CD Germanson T Shaffrey CI Jane JA. Classifications of civilian craniocerebral gunshot wounds: A multivariate analysis predictive of mortality. J Trauma 9, S279-S285. 1992. Shoung HM, Sichez JP Pertuiset B. The early prognosis of craniocerebral gunshot wounds in civilian practice as an aid to the choice of treatment. Acta Neurochirurgica 74, 27-30. 1985. Siccardi D, Cavaliere R Pau A Lubinu F Turtas S Viale GL. Penetrating craniocerebral missile injuries in civilians: A retrospective analysis of 314 cases. Surgical Neurology 35, 455-460. 1991. Sosin DM, Sacks JJ Smith SM. Head injury-associated deaths in the United States from 1979 to 1986. JAMA 262 (16), 2251-2255. 1989. Stone JL, Lichtor T Fitzgerald LF Gandhi YN. Civilian cases of tangential gunshot wounds to the head. J Trauma 41 (3), 57-60. 1996. Suddaby L, Weir B Forsyth C. The management of .22 caliber gunshot wounds of the brain: A review of 49 cases. Can J Neurol Sci 14, 268-272. 1987.

We use cookies to improve the performance of our site, to analyze the traffic to our site, and to personalize your experience of the site. You can control cookies through your browser settings. Please find more information on the cookies used on our site. Privacy Policy